122831

2-Aminobenzyl alcohol

98%

• Synonym(s): 2-(Hydroxymethyl)aniline
• Linear Formula: H₂NC₆H₄CH₂OH
• CAS Number: 5344-90-1
• Molecular Weight: 123.15
• Beilstein: 1072211
• EC Number: 226-293-7
• MDL number: MFCD00007749
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847510
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• form: solid
• bp: 162 °C/15 mmHg (lit.)
• mp: 81-83 °C (lit.)
• functional group: hydroxyl
• SMILES string: Nc1ccccc1CO
• InChI: 1S/C7H9NO/c8-7-4-2-1-3-6(7)5-9/h1-4,9H,5,8H2
• InChI key: VYFOAVADNIHPTR-UHFFFAOYSA-N

Description

General description

2-Aminobenzyl alcohol is oxidatively cyclised with an array of ketones in dioxane at 80°C in the presence of a ruthenium catalyst and KOH to give corresponding quinolines. It undergoes oxidation catalyzed by heterotrimetallic RuMnMn species on the hydrotalcite surface in the presence of O₂ to yield 2-aminobenzaldehyde.

Application

2-Aminobenzyl alcohol was used in the synthesis of ethyl 2-hydroxymethylcarbanilate.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves