142670

Chloromethyl ethyl ether

95%

• Synonym(s): (Chloromethoxy)ethane, Ethoxychloromethane, Ethoxymethyl chloride, Ethyl chloromethyl ether
• Linear Formula: C₂H₅OCH₂Cl
• CAS Number: 3188-13-4
• Molecular Weight: 94.54
• EC Number: 221-687-5
• MDL number: MFCD00000887
• UNSPSC Code: 12352101
• PubChem Substance ID: 24848532
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 95%
• form: liquid
• refractive index: n20/D 1.404 (lit.)
• bp: 82 °C (lit.)
• density: 1.019 g/mL at 25 °C (lit.)
• functional group: chloro; ether
• storage temp.: 2-8°C
• SMILES string: CCOCCl
• InChI: 1S/C3H7ClO/c1-2-5-3-4/h2-3H2,1H3
• InChI key: FCYRSDMGOLYDHL-UHFFFAOYSA-N

Description

Application

Chloromethyl ethyl ether can be used to prepare:

• 6-Benzyl-1-(ethoxymethyl)-5-iodopyrimidine-2,4(1H,3H)-dione, a key intermediate in the preparation of MKC-442 analog.
• Acylation catalyst for alcohols named 1,3-bis-[(R)-1-(2-naphthyl)ethyl]imidazoliumchloride by reacting with glyoxal-bis-[(R)-1-(2-naphthyl)ethyl]imine.

Safety Information

• Pictograms: GHS02,GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302 + H312 + H332,H319,H351
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 66.2 °F - closed cup
• Flash Point(C): 19 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves