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250260

Sigma-Aldrich

2-Naphthoyl chloride

98%

Synonym(s):

β-Naphthoyl chloride

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About This Item

Linear Formula:
C10H7COCl
CAS Number:
2243-83-6
Molecular Weight:
190.63
Beilstein:
907776
EC Number:
218-822-5
MDL number:
MFCD00004093
UNSPSC Code:
12352100
PubChem Substance ID:
24855046
NACRES:
NA.22
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Quality Level

100

Assay

98%

form

solid

bp

160-162 °C/11 mmHg (lit.)

mp

50-52 °C (lit.)

functional group

acyl chloride

SMILES string

ClC(=O)c1ccc2ccccc2c1

InChI

1S/C11H7ClO/c12-11(13)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H

InChI key

XNLBCXGRQWUJLU-UHFFFAOYSA-N

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Application

2-Naphthoyl chloride has been used in:
  • preparation of amide derivatives of the amphetamine enantiomers[1]
  • synthesis of 7-dimethylamino-2-methyl-3-naphthamido-phenothiazinium salt[2]
  • modification of self-assembled monolayer formed on silica surface from ((((aminoethyl)amino)-methyl)phenethyl)trimethoxysilane[3]

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    STBH8020
    STBH1111
    STBH0160
    STBD5486V
    S23847V

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    Fansi Jin et al.
    Allergy, 74(6), 1145-1156 (2018-12-20)
    Nuclear receptor subfamily 4 group A member 1 (NR4A1), an orphan nuclear receptor, has been implicated in several biological events such as metabolism, apoptosis, and inflammation. Recent studies indicate a potential role for NR4A1 in mast cells, yet its role

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