286281

Indole-3-acetamide

98%

• Synonym(s): 3-Indolylacetamide, NSC 1969
• Empirical Formula (Hill Notation): C₁₀H₁₀N₂O
• CAS Number: 879-37-8
• Molecular Weight: 174.20
• EC Number: 212-904-4
• MDL number: MFCD00005641
• UNSPSC Code: 12352100
• PubChem Substance ID: 24857238
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• mp: 148-150 °C (lit.)
• functional group: amide
• SMILES string: NC(=O)Cc1c[nH]c2ccccc12
• InChI: 1S/C10H10N2O/c11-10(13)5-7-6-12-9-4-2-1-3-8(7)9/h1-4,6,12H,5H2,(H2,11,13)
• InChI key: ZOAMBXDOGPRZLP-UHFFFAOYSA-N

Description

General description

Indole-3-acetamide is an auxin precursor.

Application

Indole-3-acetamide was used in the synthesis of [5.5.6.6]diazafenestrane skeleton and indole-3-acetic acid.

Reactant for the synthesis of:

• PET agent for imaging of protein kinase C
• A potential agent against Prion Disease
• Protein kinase C (PKC) inhibitor bisindolylmaleimide IV
• Glycogen synthase kinase-3ß (GSK-3ß) inhibitors
• Inhibitors of CaMKIId
• A VEGF inhibitor
• JAK3 inhibitors
• Inhibitors of NAD+-Dependent Histone Deacetylases
• Inhibitors of human adipocyte fatty acid-binding protein
• Cyclin-dependent kinase inhibitors

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves