471526

1-Dimethylamino-2-propanol

≥99%

• Synonym(s): N,N-Dimethylisopropanolamine
• Linear Formula: CH₃CH(OH)CH₂N(CH₃)₂
• CAS Number: 108-16-7
• Molecular Weight: 103.16
• Beilstein: 1209244
• EC Number: 203-556-4
• MDL number: MFCD00004532
• UNSPSC Code: 12352100
• PubChem Substance ID: 24870740
• NACRES: NA.22

Properties

• vapor density: 3.6 (vs air)
• Quality Level: 200
• vapor pressure: 8 mmHg ( 20 °C)
• Assay: ≥99%
• refractive index: n20/D 1.419 (lit.)
• bp: 121-127 °C (lit.)
• density: 0.837 g/mL at 25 °C (lit.)
• SMILES string: CC(O)CN(C)C
• InChI: 1S/C5H13NO/c1-5(7)4-6(2)3/h5,7H,4H2,1-3H3
• InChI key: NCXUNZWLEYGQAH-UHFFFAOYSA-N

Description

General description

1-Dimethylamino-2-propanol (1DMA2P, DMAPH), a tertiary amine, is a dimethylamino-alcohol having high boiling point. It is a potent protector against mechlorethamine cytotoxicity and inhibitor of choline uptake. Kinetics of homogeneous reaction of carbon dioxide (CO₂) with 1-dimethylamino-2-propanol in water has been investigated using stopped-flow technique.

Application

1-Dimethylamino-2-propanol solution may be used in the synthesis of the following:

• novel unsymmetrical 2,3,9,10,16,17,23-heptakis(alkoxyl)-24-mono(dimethylaminoalkoxyl)phthalocyanine compounds
• homoleptic nickel(II) aminoalkoxide
• Adduct with cobalt(II) 2,4-pentanedionate (acac)

Safety Information

• Pictograms: GHS02,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H226,H302,H314
• Precautionary Statements: P210 - P280 - P301 + P312 + P330 - P303 + P361 + P353 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 78.8 °F - DIN 51755 Part 1
• Flash Point(C): 26 °C - DIN 51755 Part 1
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves