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806366

Sigma-Aldrich

Poly(N-isopropyl acrylamide)

carboxylic acid, thiol

Synonym(s):

PNIPAAM, PNIPAM

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About This Item

Empirical Formula (Hill Notation):
C4H7O2(C6H11NO)nSH
UNSPSC Code:
12352100
NACRES:
NA.23
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Quality Level

form

powder

mol wt

Mn 6,000

PDI

≤1.2

storage temp.

−20°C

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This Item
195030213438227307
reaction suitability

reagent type: reductant

reaction suitability

reagent type: reductant

reaction suitability

reagent type: reductant

reaction suitability

reagent type: reductant

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

density

0.865 g/mL at 25 °C

density

0.675 g/mL at 25 °C

density

0.902 g/mL at 25 °C

density

0.866 g/mL at 25 °C

form

liquid

form

liquid

form

liquid

form

liquid

concentration

1.0 M in THF

concentration

1.0 M in hexanes

concentration

1.0 M in THF

concentration

1.0 M in toluene

Application

Novel polymer for development of thermosensitive coated micro/nano materials[1] including thermoresponsive polymeric drug delivery systems.[2] The thiol functional group can be used to conjugate to a variety of biomolecules, as well as thiol-ene click chemistry.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Multifocal and multicentric low-grade oligoastrocytoma in a young patient.
Grosu F, et al.
Romanian Journal of Morphology and Embryology, 58(1), 207-210 (2017)
Lina Chakrabarti et al.
Nature neuroscience, 13(8), 927-934 (2010-07-20)
Over-inhibition is thought to be one of the underlying causes of the cognitive deficits in Ts65Dn mice, the most widely used model of Down syndrome. We found a direct link between gene triplication and defects in neuron production during embryonic
B G Novitch et al.
Neuron, 31(5), 773-789 (2001-09-25)
Within the developing vertebrate nervous system, the mechanisms that coordinate neuronal subtype identity with generic features of neuronal differentiation are poorly defined. We show here that a bHLH protein, Olig2, is expressed selectively by motor neuron progenitors and has a
José Javier Otero et al.
Journal of neuro-oncology, 104(2), 423-438 (2011-01-05)
The bHLH transcription factor, OLIG2, is universally expressed in adult human gliomas and, as a major factor in the development of oligodendrocytes, is expressed at the highest levels in low-grade oligodendroglial tumors. In addition, it is functionally required for the

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