906301

BTTES

• Synonym(s): 3-(4-((Bis((1-(tert-butyl)-1H-1,2,3-triazol-4-yl)methyl)amino)methyl)-1H-1,2,3-triazol-1-yl)propane-1-sulfonic acid, Copper click-chemistry ligand, Water-soluble CuAAC ligand
• Empirical Formula (Hill Notation): C₂₀H₃₄N₁₀O₃S
• CAS Number: 2101505-88-6
• Molecular Weight: 494.61
• MDL number: MFCD32197457
• UNSPSC Code: 12161600

Properties

• form: solid
• reaction suitability: reaction type: click chemistry
• availability: available only in USA
• storage temp.: 2-8°C
• SMILES string: [S](=O)(=O)(O)CCC[n]1nnc(c1)CN(Cc3nn[n](c3)C(C)(C)C)Cc2nn[n](c2)C(C)(C)C
• InChI: 1S/C20H34N10O3S/c1-19(2,3)29-14-17(22-25-29)11-27(12-18-15-30(26-23-18)20(4,5)6)10-16-13-28(24-21-16)8-7-9-34(31,32)33/h13-15H,7-12H2,1-6H3,(H,31,32,33)
• InChI key: WMEZDVILBKIODK-UHFFFAOYSA-N

Description

Application

BTTES is a a next-generation, water-soluble ligand for the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that accelerates reaction rates and suppresses cell cytotoxicity. The biocompatibility and fast kinetics of BTTES are advancements from water-insoluble TBTA and are desirable for bioconjugation in diverse chemical biology experiments.

Other Notes

Sulfated Ligands for the Copper(I)-Catalyzed Azide-Alkyne Cycloaddition

Increasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study

Biocompatible copper(I) catalysts for in vivo imaging of glycans

Safety Information

• Pictograms: GHS02
• Signal Word: Danger
• Hazard Statements: H242
• Precautionary Statements: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Hazard Classifications: Self-react. C
• Storage Class Code: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable