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1.01813

Supelco

Silicate (Silicic Acid) Test

photometric, 0.5-500.0 μg/L (SiO2), 0.12-116.85 μg/L (Si), Spectroquant®

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1 MG
437,00 $
5 MG
1 020,00 $

437,00 $


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1 MG
437,00 $
5 MG
1 020,00 $

About This Item

UNSPSC Code:
41116116
NACRES:
NA.24

437,00 $


Please contact Customer Service for Availability

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product line

Spectroquant®

Quality Level

usage

sufficient for 100 tests
sufficient for 900 tests (depending on package size)

specific analyte(s)

silicate

measuring range

0.12-116.85 μg/L (Si)
0.2-233.7 μg/L (Si)
0.25-250.00 μg/L (SiO2)
0.5-500.0 μg/L (SiO2)

technique(s)

photometry: suitable

compatibility

for use with Spectroquant® Move 100
for use with Spectroquant® Nova 60 A
for use with Spectroquant® Prove 100
for use with Spectroquant® Prove 300
for use with Spectroquant® Prove 600

detection method

photometric (Silicomolybdenum blue)

storage temp.

15-25°C

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D1446SML1533C1115
ICRF-193 apoptosis inducer, arabinosidase substrate

I4659

ICRF-193

form

powder or flakes, solid

form

powder

form

powder

form

solid

assay

≥95%

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

room temp

storage temp.

−20°C

storage temp.

−20°C

solubility

DMSO: 4 mg/mL

solubility

DMSO: >20 mg/mL

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: ~4 mg/mL

biological source

synthetic (organic)

biological source

-

biological source

-

biological source

-

General description

Method: photometric 0.25 - 500.0 µg/l SiO₂ 0.12 - 233.7 µg/l Si Spectroquant®

The method is analogous to APHA 4500-SiO2 D+E, ASTM D859-10, and DIN 38405-21.

This Spectroquant® Silicate Reagent Test allows the accurate quantification of silicate (silicic acid) in aqueous samples.

Method applied: In sulfuric solution silicate ions react with molybdate ions to form a yellow heteropoly acid which is reduced to silicomolybdenum blue. This dye is determined photometrically.

The Spectroquant® Reagent Test Kits contain highly stable, ready-to-use reagent mixtures to perform the analysis according to the procedure described in the accompanying instruction leaflet.

All our Cell and Reagent Test Kits are equipped with the unique Live ID (2D barcode) which allows seamless method recognition and contains essential information such as lot number, expiry date, and automatic calibration updates.

Legal Information

SPECTROQUANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A - Skin Sens. 1

Supplementary Hazards

Storage Class Code

8B - Non-combustible, corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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ICRF-193, a catalytic inhibitor of DNA topoisomerase II, delays the cell cycle progression from metaphase, but not from anaphase to the G1 phase in mammalian cells
Iwai M, et al.
Febs Letters, 406(3), 267-270 (1997)
N Hajji et al.
Mutation research, 530(1-2), 35-46 (2003-10-18)
The bis-dioxopiperazine ICRF-193 has long time been considered as a pure topoisomerase II catalytic inhibitor able to exert its inhibitory effect on the enzyme without stabilization of the so-called cleavable complex formed by DNA covalently bound to topoisomerase II. In
The catalytic DNA topoisomerase II inhibitor ICRF-193 and all-trans retinoic acid cooperatively induce granulocytic differentiation of acute promyelocytic leukemia cells: candidate drugs for chemo-differentiation therapy against acute promyelocytic leukemia
Niitsu,
Experimental Hematology, 30(11), 1273-1282 (2002)
K C Huang et al.
The Journal of biological chemistry, 276(48), 44488-44494 (2001-09-29)
Antineoplastic bis(dioxopiperazine)s, such as meso-2,3-bis(2,6-dioxopiperazin-4-yl)butane (ICRF-193), are widely believed to be only catalytic inhibitors of topoisomerase II. However, topoisomerase inhibitors have little or no antineoplastic activity unless they are topoisomerase poisons, a special subclass of topoisomerase-targeting drugs that stabilize topoisomerase-DNA
Sílvia Dyson et al.
The EMBO journal, 40(1), e105393-e105393 (2020-11-07)
The juxtaposition of intracellular DNA segments, together with the DNA-passage activity of topoisomerase II, leads to the formation of DNA knots and interlinks, which jeopardize chromatin structure and gene expression. Recent studies in budding yeast have shown that some mechanism

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