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About This Item
Empirical Formula (Hill Notation):
C14H16N2O6
CAS Number:
Molecular Weight:
308.29
Beilstein:
1499815
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.25
Quality Level
Assay
≥98.0% (HPLC)
form
solid
reaction suitability
reagent type: linker
mp
67-73 °C
70-73 °C (lit.)
functional group
NHS ester
storage temp.
−20°C
SMILES string
O=C(ON(C(CC1)=O)C1=O)CCCCCN2C(C=CC2=O)=O
InChI
1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
InChI key
VLARLSIGSPVYHX-UHFFFAOYSA-N
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Application
6-Maleimidohexanoic acid N-hydroxysuccinimide ester is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
Reagent for cross-linking and immobilisation of proteins
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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