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Sigma-Aldrich

Laminin Mimetic animal-free ECM peptides

MAPTRIX-L-RKRLQVQLSIRT, solution, 0.5 mg/mL protein, suitable for cell culture

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20 MG
₩207,162

About This Item

UNSPSC Code:
12352202
NACRES:
NA.75

₩207,162

Please contact Customer Service for Availability
Request a Bulk Order
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Product Name

MAPTRIX-L-RKRLQVQLSIRT, Laminin Mimetic, aqueous solution

sterility

Filtered sterilized solution

form

aqueous solution

mol wt

~24.1 kDa

packaging

pkg of 2.5 mg

concentration

0.5 mg/mL protein

technique(s)

cell culture | mammalian: suitable

Binding Specificity

Receptor: Syndecan-1, -4
Domain: α1 LG4 - AG73
Binding Motif: RKRLQVQLSIRT

shipped in

ambient

storage temp.

2-8°C

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SAB1405195HPA072387SAB1403075
Monoclonal Anti-DPYSL5 antibody produced in mouse clone 2G4, purified immunoglobulin, buffered aqueous solution

SAB1400644

Monoclonal Anti-DPYSL5 antibody produced in mouse

Monoclonal Anti-DPYSL5 antibody produced in mouse clone 2D10, purified immunoglobulin, buffered aqueous solution

SAB1405195

Monoclonal Anti-DPYSL5 antibody produced in mouse

Anti-DPYSL5 antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody

HPA072387

Anti-DPYSL5 antibody produced in rabbit

Monoclonal Anti-DPYSL4 antibody produced in mouse clone 1F5, purified immunoglobulin, buffered aqueous solution

SAB1403075

Monoclonal Anti-DPYSL4 antibody produced in mouse

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

mouse

biological source

mouse

biological source

rabbit

biological source

mouse

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

species reactivity

human

species reactivity

human, rat

species reactivity

human

species reactivity

human

Gene Information

human ... DPYSL5(56896)

Gene Information

human ... DPYSL5(56896)

Gene Information

human ... DPYSL5(56896)

Gene Information

human ... DPYSL4(10570)

clone

2G4, monoclonal

clone

2D10, monoclonal

clone

polyclonal

clone

1F5, monoclonal

Application

MAPTrix™ Technology provides a true extracellular microenvironment (ECM) by presenting combinatorial peptide motifs. The ECM, defined by biochemical cues and physical cues, is a deciding factor in a wide range of cellular processes including cell adhesion, proliferation, differentiation, and expression of phenotype-specific functions.Currently existing technology offers simple and merely adequate environments that facilitate simple cell processes such as cellular adhesion.[1][2] The simple presentation of cell adhesion motifs is not optimal for controlling more integrated processes. Crosstalk among signaling pathways act synergistically to enhance cellular responses such as cell adhesion or proliferation.[3] A study showed that a combination of extracellular matrix derived peptides presented on a surface may enhance cell adhesion strength and focal adhesion assembly. The combinatorial presentation of ECM peptides on cell growth surfaces may also promote elevated proliferation rates of primary or stem cells.[4][5][6]

Features and Benefits

  • Biochemically-defined, animal-free cell culture surfaces designed to enhance cell performance
  • MAPTrix™ produces a uniform ECM surface that provides a highly controlled 2D extracellular microenvironment for cell cultures and related applications
  • Adhesion properties of the mussel adhesive protein makes the coating reproducible & reliable

Legal Information

MAPTrix is a trademark of Kollodis Biosciences

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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    Stefano Fogli et al.
    Pharmacological research, 76, 149-156 (2013-08-21)
    Microparticles (MPs) are membrane fragments that may play a role in the pathogenesis of chronic respiratory diseases. We aimed to investigate whether human monocytes/macrophage-derived MPs could induce a pro-inflammatory phenotype in human bronchial smooth muscle cells (BSMC) and the effect
    Chenghua Zhou et al.
    Anesthesia and analgesia, 118(5), 1090-1096 (2014-04-02)
    Cysteinyl leukotrienes and their receptors have been shown to be involved in the generation of neuropathic pain. We performed this study to determine the antagonistic effect of montelukast, a cysteinyl leukotrienes receptor antagonist, on neuropathic pain and its underlying mechanism.
    Yves Pacheco et al.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 51(1), 1-17 (2013-07-10)
    Rhinitis and other specific triggers or co-morbidities (tobacco exposure, excess weight, aspirin sensitivity or heredity factors) are frequently associated with uncontrolled asthma. Asthma associated with these exacerbating factors appears to be related to an increase in leukotriene-mediated inflammation. We reviewed
    Xiaoju Tang et al.
    American journal of respiratory cell and molecular biology, 49(6), 960-970 (2013-07-05)
    Foxa2 is a member of the Forkhead family of nuclear transcription factors that is highly expressed in respiratory epithelial cells of the developing and mature lung. Foxa2 is required for normal airway epithelial differentiation, and its deletion causes goblet-cell metaplasia
    Genyo Ikeda et al.
    American journal of respiratory cell and molecular biology, 50(1), 18-29 (2013-08-14)
    The incidence of overlapping bronchial asthma and chronic obstructive pulmonary disease has increased in recent years. Cysteinyl leukotrienes (CysLTs) play an important role in asthma, and the type 1 CysLT receptor (CysLT1R) is expressed by many inflammatory cells. We evaluated
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