Skip to Content
Merck

Skip To

168024K

Sigma-Aldrich

MAPTRIX-V-KKQRFRHRNRKGY

Vitronectin Mimetic, aqueous solution

Sign Into View Organizational & Contract Pricing

About This Item

UNSPSC Code:
12352202
NACRES:
NA.75
Pricing and availability is not currently available.
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

sterility

Filtered sterilized solution

form

aqueous solution

mol wt

~24.7 kDa

packaging

pkg of 10 mg

concentration

1.0 mg/mL protein

technique(s)

cell culture | mammalian: suitable

Binding Specificity

Receptor: Heparin
Domain: HBV
Binding Motif: KKQRFRHRNRKGYRSQ

shipped in

ambient

storage temp.

2-8°C

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
SAB2102228SAB4300781SAB5200103
conjugate

unconjugated

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

product line

Prestige Antibodies® Powered by Atlas Antibodies

product line

-

product line

-

product line

-

Gene Information

human ... SLCO2B1(11309)

Gene Information

human ... SLCO2B1(11309)

Gene Information

human ... SLCO1B1(10599)

Gene Information

rat ... Slc12a1(25065)

Application

MAPTrix Technology provides a true extracellular microenvironment (ECM) by presenting combinatorial peptide motifs. The ECM, defined by biochemical cues and physical cues, is a deciding factor in a wide range of cellular processes including cell adhesion, proliferation, differentiation, and expression of phenotype-specific functions.Currently existing technology offers simple and merely adequate environments that facilitate simple cell processes such as cellular adhesion.[1][2] The simple presentation of cell adhesion motifs is not optimal for controlling more integrated processes. Crosstalk among signaling pathways act synergistically to enhance cellular responses such as cell adhesion or proliferation.[3] A study showed that a combination of extracellular matrix derived peptides presented on a surface may enhance cell adhesion strength and focal adhesion assembly. The combinatorial presentation of ECM peptides on cell growth surfaces may also promote elevated proliferation rates of primary or stem cells.[4][5][6]

Features and Benefits

  • Biochemically-defined, animal-free cell culture surfaces designed to enhance cell performance
  • MAPTrix produces a uniform ECM surface that provides a highly controlled 2D extracellular microenvironment for cell cultures and related applications
  • Adhesion properties of the mussel adhesive protein makes the coating reproducible & reliable

Legal Information

MAPTrix is a trademark of Kollodis Biosciences

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Michael J Knauer et al.
Molecular pharmacology, 83(6), 1218-1228 (2013-03-28)
Human organic anion transporting polypeptide 2B1 (OATP2B1) is a membrane transporter that facilitates the cellular uptake of a number of endogenous compounds and drugs. OATP2B1 is widely expressed in tissues including the small intestine, liver, kidney, placenta, heart, skeletal muscle
Kyoung-Ah Kim et al.
Journal of clinical pharmacology, 53(11), 1186-1193 (2013-08-24)
Montelukast, a leukotriene receptor antagonist, is a substrate of organic anion transporting OATP2B1 encoded by the SLCO2B1. We evaluated the effects of six non-synonymous (c.1175C>T, c.1457C>T, c.43C>T, c.935G>A, c.601G>A, and c.644A>T) polymorphisms and one promoter (g.-282G>A) polymorphism on the pharmacokinetics

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service