A7223

Albumin human

recombinant, expressed in Pichia pastoris, 5% in aqueous buffer, ≥90% (SDS-PAGE)

• Synonym(s): Albagen^™, rHSA
• Empirical Formula (Hill Notation): C₂₉₃₆H₄₆₂₄N₇₈₆O₈₈₉S₄₁
• CAS Number: 70024-90-7
• Molecular Weight: 66471.53
• MDL number: MFCD00081418
• UNSPSC Code: 12352202
• NACRES: NA.25

Properties

• biological source: human
• Quality Level: 200
• recombinant: expressed in Pichia pastoris
• Assay: ≥90% (SDS-PAGE)
• form: solution
• mol wt: monomer ~67 kDa
• concentration: 5% in aqueous buffer
• technique(s): cell culture | mammalian: suitable
• UniProt accession no.: P02768
• shipped in: wet ice
• storage temp.: 2-8°C
• SMILES string: FC(F)(F)C(F)(F)C(F)(F)F
• InChI: 1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
• InChI key: QYSGYZVSCZSLHT-UHFFFAOYSA-N
• Gene Information: human ... ALB(213)

Description

Application

This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells.

Biochem/physiol Actions

Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.

Physical properties

Recombinant construct with N-terminal deletion of Asp. Structurally equivalent to native albumin by x-ray crystallography. The N-terminal Asp is the principal Cu²⁺ and Ni²⁺ chelation site; its deletion eliminates an important antigenic determinant, and the protein is hypoallergenic. Also blocked at Cys³⁴ to improve stability, monomer content and homogeneity.

Physical form

Solution in phosphate buffered saline containing 4 mM sodium caprylate and 4 mM N-acetyltryptophan.

Other Notes

View more information on human serum albumin.

Legal Information

Albagen is a trademark of Albumin Therapeutics, LLC.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable