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A9227

Sigma-Aldrich

ABT-491 hydrochloride

≥98% (HPLC)

Synonym(s):

4-Ethynyl-N,N-dimethyl-3-[3-fluoro-4-[(2-methyl-1H-imidazo-[4,5-c]pyridin-1-yl)methyl]benzoyl]-1H-indole-1-carboxamide hydrochloride, A-137491

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1 G
₹21,076.00

About This Item

Empirical Formula (Hill Notation):
C28H22N5O2F · HCl
CAS Number:
189689-94-9
Molecular Weight:
515.97
MDL number:
MFCD00945301
UNSPSC Code:
12352200
PubChem Substance ID:
24724404
NACRES:
NA.77

₹21,076.00

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Quality Level

100

Assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

white to beige

mp

170-178 °C (lit.)

solubility

H2O: freely soluble 22 mg/mL

originator

Abbott

storage temp.

2-8°C

SMILES string

Cl[H].CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)c(F)c2)c5c(cccc15)C#C

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1 of 4

This Item
SML0346G3796S1697
ABT-491 hydrochloride ≥98% (HPLC)

A9227

ABT-491 hydrochloride

Alosetron hydrochloride ≥98% (HPLC)

SML0346

Alosetron hydrochloride

Granisetron hydrochloride ≥98% (HPLC), solid

G3796

Granisetron hydrochloride

SPD304 ≥98% (HPLC), solid

S1697

SPD304

form

solid

form

powder

form

solid

form

solid

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

room temp

storage temp.

2-8°C

solubility

H2O: freely soluble 22 mg/mL

solubility

H2O: ≥5 mg/mL at warmed

solubility

H2O: >10 mg/mL

solubility

H2O: >5 mg/mL

storage condition

desiccated

storage condition

desiccated

storage condition

desiccated

storage condition

-

Biochem/physiol Actions

Highly potent, selective and orally active platelet-activating factor (PAF) receptor antagonist. Ki = 0.6 nM in human platelets.

Features and Benefits

This compound is featured on the PAF Receptor page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    036K4708V
    036K47082
    036K47081
    053K4710
    036K4708

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