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EHU140371

Sigma-Aldrich

MISSION® esiRNA

targeting human UPF2

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TCCTCAAGACAAACCAACACCAGAAGAACATGGGCCTGGAATTGATATATTCACACCTGGTAAACCTGGAGAATATGACTTGGAAGGTGGTATATGGGAAGATGAAGATGCTCGGAATTTTTATGAGAACCTCATTGATTTGAAGGCTTTTGTCCCAGCCATCTTGTTTAAAGACAATGAAAAAAGTTGTCAGAATAAAGAGTCCAACAAAGATGATACCAAAGAGGCAAAAGAATCTAAGGAGAATAAGGAGGTATCAAGTCCCGATGATTTGGAACTTGAGTTGGAGAATCTAGAAATTAATGATGACACCTTAGAATTAGAGGGTGGAGATGAAGCTGAAGATCTTACAAAGAAACTTCTTGATGAACAAGAACAAGAAGATGAGGAAGCCAGCACTG

Ensembl | human accession no.

ENSG00000151461

NCBI accession no.

NM_015542

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... UPF2(26019), UPF2(26019)

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EHU143841EHU085961EHU160201
MISSION® esiRNA targeting human UPF2

EHU140371

MISSION® esiRNA

MISSION® esiRNA targeting human LRIG1

EHU143841

MISSION® esiRNA

MISSION® esiRNA targeting human RPAP1

EHU085961

MISSION® esiRNA

MISSION® esiRNA targeting human ERC2 (2)

EHU160201

MISSION® esiRNA

Ensembl | human accession no.

ENSG00000151461

Ensembl | human accession no.

ENSG00000144749

Ensembl | human accession no.

ENSG00000103932

Ensembl | human accession no.

ENSG00000187672

Gene Information

human ... UPF2(26019), UPF2(26019)

Gene Information

human ... LRIG1(26018), LRIG1(26018)

Gene Information

human ... RPAP1(26015), RPAP1(26015)

Gene Information

human ... ERC2(26059), ERC2(26059)

esiRNA cDNA target sequence

TCCTCAAGACAAACCAACACCAGAAGAACATGGGCCTGGAATTGATATATTCACACCTGGTAAACCTGGAGAATATGACTTGGAAGGTGGTATATGGGAAGATGAAGATGCTCGGAATTTTTATGAGAACCTCATTGATTTGAAGGCTTTTGTCCCAGCCATCTTGTTTAAAGACAATGAAAAAAGTTGTCAGAATAAAGAGTCCAACAAAGATGATACCAAAGAGGCAAAAGAATCTAAGGAGAATAAGGAGGTATCAAGTCCCGATGATTTGGAACTTGAGTTGGAGAATCTAGAAATTAATGATGACACCTTAGAATTAGAGGGTGGAGATGAAGCTGAAGATCTTACAAAGAAACTTCTTGATGAACAAGAACAAGAAGATGAGGAAGCCAGCACTG

esiRNA cDNA target sequence

AGTTGACAGCGGTACCATCCCTGGGCGCTGCTTCATCACATGTCGTCTCTCTCTTTCTGCAGCACAACAAGATTCGCAGCGTGGAGGGGAGCCAGCTGAAGGCCTACCTTTCCTTAGAAGTGTTAGATCTGAGTTTGAACAACATCACGGAAGTGCGGAACACCTGCTTTCCACACGGACCGCCTATAAAGGAGCTCAACCTGGCAGGCAATCGGATTGGCACCCTGGAGTTGGGAGCATTTGATGGTCTGTCACGGTCGCTGCTAACTCTTCGCCTGAGCAAAAACAGGATCACCCAGCTTCCTGTAAGAGCATTCAAGCTACCCAGGCTGACACAACTGGACCTCAATCGGAACAGGATTCGGCTGATAGAGGGCCTCACCTTCCAGGGGCTCAACAGCTTGGAGGTGCTGAAGCTTC

esiRNA cDNA target sequence

ACCTGCTGCACTTCCAGAGTCAGTTTCTCGCAGCTGGTGCAGCCCCAGCAGTGCAGTTGGTGAAGAAAGGAAATAGGGGCGGTGGTGATGCCAACTCAGACCGGCCTCCGCTCCAGGACCATCGGGATGTGGTGATGTTGGACAATCTCCCAGATTTGCCCCCAGCTTTGGTCCCTTCTCCTCCAAAGAGAGCCAGGCCCAGCCCTGGCCACTGCCTGCCTGAGGATGAGGACCCAGAAGAGAGGCTGAGGAGGCATGATCAGCACATCACTGCTGTCTTGACTAAGATTATTGAACGAGATACAAGTTCAGTGGCCGTGAATCTGCCTGTGCCCAGTGGTGTTGCTTTCCCTGCTGTGTTCCTTCGCTCGCGGGACACACAGGGGAAATCAGCAACATCTGGTAAGAGAAGCATCTTTGCCCAGGAAATTG

esiRNA cDNA target sequence

TGGAGGAACAGGCAAGACTCTGTCTATGGAGAATATCCAGTCCCTCAATGCAGCCTATGCTACGTCTGGACCCATGTATCTGAGTGATCATGAAGGGGTGGCTTCAACAACCTACCCAAAGGGCACTATGACTCTGGGAAGGGCTACAAATCGAGCTGTATATGGAGGCCGTGTCACAGCCATGGGGAGTAGTCCCAATATTGCTTCTGCTGGACTTTCCCACACAGATGTCCTTTCATACACAGATCAACATGGTGGGCTGACTGGCTCATCCCATCATCACCACCACCAGGTCCCCTCCATGTTGAGGCAGGTAAGAGACAGCACAATGTTAGATCTTCAGGCCCAGCTGAAAGAACTGCAGAGAGAGAATGACCTCCTCCGGAAAGAGCTAGACATCAAGGACAGCAAATTGGGAT

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

NCBI accession no.

NM_015542

NCBI accession no.

NM_015541

NCBI accession no.

NM_015540

NCBI accession no.

NM_015576

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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    Jieshuang Jia et al.
    Journal of cell science, 130(18), 3009-3022 (2017-07-27)
    Nonsense-mutation-containing messenger ribonucleoprotein particles (mRNPs) transit through cytoplasmic foci called P-bodies before undergoing nonsense-mediated mRNA decay (NMD), a cytoplasmic mRNA surveillance mechanism. This study shows that the cytoskeleton modulates transport of nonsense-mutation-containing mRNPs to and from P-bodies. Impairing the integrity

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