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About This Item
Empirical Formula (Hill Notation):
C10H15N5O11P2
CAS Number:
Molecular Weight:
443.20
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
biological source
synthetic (organic)
Quality Level
type
Type I
Assay
≥96% (HPLC)
form
powder
shipped in
dry ice
storage temp.
−20°C
SMILES string
[Na].NC1=NC(=O)c2ncn(C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O)c2N1
InChI
1S/C10H15N5O11P2.Na.H/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18);;
InChI key
PVMPTWQLNDHIEV-UHFFFAOYSA-N
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Application
Guanosine 5′-diphosphate sodium salt has been used:
- in GTP-γ-35S functional assays
- in Y1 agonist-stimulated [35S]- guanosine-5′-O-(3-thio)triphosphate (GTPγS) functional binding
- in the expression and purification of recombinant proteins
Biochem/physiol Actions
Guanosine 5′-diphosphate (GDP) is the diphosphate nucleoside of the purine guanine. GDP and GTP are involved in and may be used to study cell signaling via G-coupled protein receptors (GCPR) and guanine nucleotide exchange factors (GEF) and a variety of GTPases.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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