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Key Documents

L6638

Sigma-Aldrich

Lipid A, monophosphoryl from Escherichia coli F583 (Rd mutant)

lyophilized powder

Synonym(s):

E. coli Monophosphoryl Lipid A

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About This Item

MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25

biological source

Escherichia coli (F583 Rd mutant)

Quality Level

form

lyophilized powder

impurities

<0.2% Ketodeoxyoctonate (KDO)

shipped in

ambient

storage temp.

2-8°C

Related Categories

Biochem/physiol Actions

Lipid A has immunostimulatory adjuvant activity including macrophage, T-cell, and B-cell activation. Research has shown Lipid A has greater Th1 than Th2 stimulation.
Lipid A molecules compose the lipid membrane anchoring core components of endotoxins produced by Gram-negative bacteria. Lipid A molecules induce immune responses. Structually, lipid A molecules are composed of two glucosamine unites with varied, species dependent, fatty acyl chain number and identity and degree of phosphorylation.
Lipid A, monophosphoryl from Escherichia coli F583 may be used in comparative assessment of the antigenicity of specific structures within different LPA molecules and analogues.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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