M7898
Monoclonal Anti-Thy 1.1 antibody produced in mouse
clone TN-26, purified immunoglobulin, buffered aqueous solution
Synonym(s):
Anti-CD90, Anti-CDw90
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Recommended Products
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
TN-26, monoclonal
form
buffered aqueous solution
species reactivity
mouse
technique(s)
complement-mediated cytotoxicity assay: suitable
indirect immunofluorescence: suitable
isotype
IgM
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
mouse ... Thy1(21838)
General description
Monoclonal Anti-Thy 1.1 (mouse IgM isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.
Thymus cell antigen 1 (Thy 1.1) is a glycosylphosphatidyl-anchored protein. It belongs to the of the immunoglobulin superfamily. Thy 1.1 is expressed in stem cells, T-cells and neurons.
Specificity
Recognizes Thy 1.1 bearing cells and is less than 5% cross-reactive with Thy 1.2 bearing cells. Titer is 1:20,000 as determined by in vitro cytotoxicity against AKR/J thymocytes.
Immunogen
thymocytes from AKR/J (Thy 1.1) mice.
Application
Monoclonal Anti-Thy 1.1 antibody produced in mouse has been used in immunopanning and immunofluorescence.
Biochem/physiol Actions
Studies have shown that mice lacking the protein thymus cell antigen 1 (Thy 1.1) have an increased number of fibroblasts. It suppresses proliferation and enhances apoptosis in dermal fibroblasts, thereby modulating cell growth. This is carried out by regulating the action of β3 integrin.
Physical form
Solution in 0.1 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service