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About This Item
Empirical Formula (Hill Notation):
C5H12N2O2 · HCl
CAS Number:
Molecular Weight:
168.62
Beilstein:
3625847
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.75
biological source
microbial
Quality Level
product line
BioReagent
Assay
≥99%
form
powder
packaging
pkg of 100 g
pkg of 25 g
technique(s)
cell culture | mammalian: suitable
impurities
ammonia and citrulline, essentially free
solubility
H2O: soluble 50 mg/mL, clear, colorless to very faintly yellow
SMILES string
Cl.NCCC[C@H](N)C(O)=O
InChI
1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1
InChI key
GGTYBZJRPHEQDG-WCCKRBBISA-N
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General description
L-Ornithine is the functional metabolite of L-arginine.
L-Ornithine is an amino acid that is not coded for by the genetic code. It is formed during the decomposition of argininine by arginase and participates in the urea cycle. Ornithine is the starting point for the formation of a family of polyamines that include spermine, spermidine and putrescine.
Application
L-Ornithine monohydrochloride has been used:
- as a supplement in Dulbecco′s modified eagle medium (DMEM) for cell growth assays
- as a component in the standard medium for primary human hepatocytes (PHH) culture
- as a creatine synthesis inhibitor
Biochem/physiol Actions
L-ornithine acts as a precursor for polyamines. It may modulate the intake of food as an acute satiety signal in the neonatal chick brain.
L-Ornithine is used as a media supplement to support the biosynthesis of polyamines.
Other Notes
Product of arginine degradation by arginase
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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