SMB00174

Cirsimaritin

≥90% (LC/MS-ELSD)

• Synonym(s): 4′,5-Dihydroxy-6,7-dimethoxyflavone, Skrofulein
• Empirical Formula (Hill Notation): C₁₇H₁₄O₆
• CAS Number: 6601-62-3
• Molecular Weight: 314.29
• MDL number: MFCD00238561
• UNSPSC Code: 12352200
• PubChem Substance ID: 329824840
• NACRES: NA.25

Properties

• Assay: ≥90% (LC/MS-ELSD)
• form: solid
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: −20°C
• SMILES string: COc1cc2OC(=CC(=O)c2c(O)c1OC)c3ccc(O)cc3
• InChI: 1S/C17H14O6/c1-21-14-8-13-15(16(20)17(14)22-2)11(19)7-12(23-13)9-3-5-10(18)6-4-9/h3-8,18,20H,1-2H3
• InChI key: ZIIAJIWLQUVGHB-UHFFFAOYSA-N

Description

General description

Natural product derived from plant source.

Biochem/physiol Actions

Cirsimaritin has been shown to inhibit tumor cell growth and induce mitochondrial apoptosis in GBC-SD cells. It was proposed that cirsimaritin-induced reactive oxygen species is the trigger for ER stress and down-regulate the phosphorylation of Akt.

Safety Information

• Pictograms: GHS06,GHS09
• Signal Word: Danger
• Hazard Statements: H301,H410
• Precautionary Statements: P273 - P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable