Sign Into View Organizational & Contract Pricing
About This Item
Empirical Formula (Hill Notation):
C19H15NOS2
CAS Number:
Molecular Weight:
337.46
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Quality Level
Assay
≥98% (HPLC)
form
powder
color
yellow
solubility
DMSO: ≥25 mg/mL
storage temp.
2-8°C
SMILES string
Cc1ccccc1N2C(=S)S\C(=C\C=C\c3ccccc3)C2=O
InChI
1S/C19H15NOS2/c1-14-8-5-6-12-16(14)20-18(21)17(23-19(20)22)13-7-11-15-9-3-2-4-10-15/h2-13H,1H3/b11-7+,17-13+
InChI key
UYZLENPCNZVWQZ-QHMSGILQSA-N
Application
IMB-10 may be used to study integrin-mediated signaling in tumor cells.
Biochem/physiol Actions
IMB-10 is a ligand for the αMβ2 integrin that stabilizes the binding of the integrin to endogenous ligands such as proMMP-9 and fibrinogen. IMB-10 blocks migration of lymphocyte cell lines and inhibits leukocyte infiltration in a murine thioglycolate-induced peritonitis.
IMB-10 is a thioxothiazolidine compound that inhibits the infiltration of leukocytes to the site of tumor and blocks the invasion of HSC-3 carcinoma. It modulates the host inflammatory responses and tumor progression.
Stabilizing Ligand of αMβ2 integrin
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service