SML0351

CPDT

≥96% (HPLC)

• Synonym(s): 5,6-Dihydro-Cyclopenta[c]-1,2-dithiole-3(4H)-thione, CJ 11788, SNU2A
• Empirical Formula (Hill Notation): C₆H₆S₃
• CAS Number: 14085-33-7
• Molecular Weight: 174.31
• MDL number: MFCD00799281
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825354
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥96% (HPLC)
• form: powder
• color: faintly red to very dark red
• solubility: DMSO: 2 mg/mL (warmed)
• storage temp.: 2-8°C
• SMILES string: S=C1SSC2=C1CCC2
• InChI: 1S/C6H6S3/c7-6-4-2-1-3-5(4)8-9-6/h1-3H2
• InChI key: AVSGTGUIBQOXJK-UHFFFAOYSA-N

Description

Application

5,6-dihydrocyclopenta-1,2-dithiole-3-thione (CPDT) has been used to study its protective effects and the underlying mechanism in diabetic cardiomyopathy.

Biochem/physiol Actions

5,6-dihydrocyclopenta-1,2-dithiole-3-thione (CPDT) is a phase II enzyme inducer. It exhibits protective actions against chemical carcinogens.

CPTD (SNU2A) is a cytoprotective agent that protects mitochondria during cell stress by increasing antioxidant capacity. CPTD inhibits phosphorylation and activation of Fyn, which maintains AMPK activity and activation of Nrf2.

CPTD is an anti-oxidant, cytoprotective agent.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301,H412
• Precautionary Statements: P264 - P270 - P273 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 3
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable