Skip to Content
MilliporeSigma

Skip To

SML0945

Sigma-Aldrich

Nilvadipine

≥98% (HPLC)

Synonym(s):

2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl 5-(1-methylethyl) ester, 5-Isopropyl-3-methyl-2-cyano-1,4-dihydro-6-methyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate, FK-235, FR-34235, Isopropyl 6-cyano-5-methoxycarbonyl-2-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate, Nivadipine, Nivaldipine, SKF-102362

Sign Into View Organizational & Contract Pricing

Select a Size

100 μG
677,00 $

677,00 $


Please contact Customer Service for Availability
A recombinant, preservative-free antibody is available for your target. Try ZMS05636

Request a Bulk Order

Select a Size

Change View
100 μG
677,00 $

About This Item

Empirical Formula (Hill Notation):
C19H19N3O6
CAS Number:
Molecular Weight:
385.37
UNSPSC Code:
12352200
NACRES:
NA.77

677,00 $


Please contact Customer Service for Availability
A recombinant, preservative-free antibody is available for your target. Try ZMS05636

Request a Bulk Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 15 mg/mL, clear

storage temp.

room temp

SMILES string

[N+](=O)([O-])c1cc(ccc1)C2C(=C(NC(=C2C(=O)OC)C#N)C)C(=O)OC(C)C

InChI

1S/C19H19N3O6/c1-10(2)28-19(24)15-11(3)21-14(9-20)17(18(23)27-4)16(15)12-6-5-7-13(8-12)22(25)26/h5-8,10,16,21H,1-4H3

InChI key

FAIIFDPAEUKBEP-UHFFFAOYSA-N

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
15018AST15019AST15020AST
separation technique

chiral

separation technique

chiral

separation technique

chiral

separation technique

chiral

particle size

5 μm

particle size

5 μm

particle size

5 μm

particle size

5 μm

matrix active group

vancomycin phase

matrix active group

vancomycin phase

matrix active group

vancomycin phase

matrix active group

vancomycin phase

L × I.D.

15 cm × 4.6 mm

L × I.D.

10 cm × 2.1 mm

L × I.D.

15 cm × 2.1 mm

L × I.D.

25 cm × 2.1 mm

product line

Astec®

product line

Astec®

product line

Astec®

product line

Astec®

technique(s)

HPLC: suitable, LC/MS: suitable

technique(s)

HPLC: suitable, LC/MS: suitable

technique(s)

HPLC: suitable, LC/MS: suitable

technique(s)

HPLC: suitable, LC/MS: suitable

General description

Nilvadipine is a dihydropyridine drug.[1]

Biochem/physiol Actions

Nilvadipine is a potent calcium channel blocker that is used for treatment of hypertension. Nilvadipine, as other dihydropyridine calcium antagonists, decreases intracellular calcium concentration causing dilation of the coronary and systemic arteries. Nilvadipine acutely reduced brain Aβ levels in a transgenic mouse model of Alzheimer′s disease (AD).
Nilvadipine is a potent calcium channel blocker; antihypertensive; antianginal.
Nilvadipine, apart from its antihypertensive effect, is known to decrease the accumulation of β-amyloid protein in the brain. Therefore, it is effective in the treatment of Alzheimer′s disease. Nilvadipine also promotes cognitive function in hypertensive patients.[1]

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


  • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service