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T7677

Sigma-Aldrich

L-Tyrosine Decarboxylase from Streptococcus faecalis

≥0.1 unit/mg solid

Synonym(s):

L-Tyrosine carboxy-lyase

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About This Item

CAS Number:
9002-09-9
EC Number:
4.1.1.25 (BRENDA, IUBMB)
EC Number:
232-652-9
MDL number:
MFCD00131472
UNSPSC Code:
12352204
NACRES:
NA.54
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form

powder

Quality Level

200

specific activity

≥0.1 unit/mg solid

storage temp.

−20°C

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Application

L-Tyrosine decarboxylase from Streptococcus faecalis has been used in a study to isolate and identify the carbonyl-active site of diamine oxidase by gas chromatographic mass spectrometry. [1] L-Tyrosine decarboxylase from Streptococcus faecalis has also been used in a study to investigate the adsorption of Streptococcus faecalis on diatomite carriers for use in biotransformations. [2]

Other Notes

Dried cells from which activity can be extracted.

Unit Definition

One unit will cause the decomposition of 1.0 μmole of L-tyrosine per min at pH 6.2 at 37 °C.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    SLBW6926
    SLBK5194V
    SLBF2216V
    117K1527
    076K1530

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    Kazuhisa Nakano et al.
    Journal of immunology (Baltimore, Md. : 1950), 190(3), 1297-1303 (2013-01-02)
    Rheumatoid arthritis (RA) is a chronic inflammatory disease in which fibroblast-like synoviocytes (FLS) exhibit an aggressive phenotype. Although the mechanisms responsible are not well defined, epigenetic determinants such as DNA methylation might contribute. DNA methyltransferases (DNMTs) are critical enzymes that
    Vitalina M Komashko et al.
    Epigenetics, 5(3), 229-240 (2010-03-23)
    Methylation of DNA in combination with histone modifications establishes an epigenetic code that ensures the proper control of gene expression. Although DNA methyltransferases have been shown to interact with histone methyltransferases such as EZH2 (which methylates histone H3 on lysine
    INSIG2 rs7566605 single nucleotide variant and global DNA methylation index levels are associated with weight loss in a personalized weight reduction program
    Pirini F, et al.
    Molecular Medicine Reports, 17(1), 1699-1709 (2018)
    Rafael Guerrero-Preston et al.
    Epigenetics, 5(6), 539-546 (2010-06-05)
    Environmental exposures in-utero may alter the epigenome, thus impacting chromosomal stability and gene expression. We hypothesized that in utero exposures to maternal smoking and perfluoroalkyl compounds (PFCs) are associated with global DNA hypomethylation in umbilical cord serum. Our objective was
    Magdalena Gryzinska et al.
    Biochemical genetics, 51(7-8), 554-563 (2013-04-05)
    DNA methylation is an epigenetic modification that plays an important role in the normal development and function of organisms. The level of DNA methylation is species-, tissue-, and organelle-specific, and the methylation pattern is determined during embryogenesis. DNA methylation has
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