V0377

[Arg⁸]-Vasopressin solution

Grade VI (synthetic), ~100 IU/mL in 0.9% NaCl

• Synonym(s): β-Hypophamine, AVP, Antidiuretic hormone, Arginine vasopressin
• Empirical Formula (Hill Notation): C₄₆H₆₅N₁₅O₁₂S₂
• CAS Number: 113-79-1
• Molecular Weight: 1084.23
• MDL number: MFCD00076738
• UNSPSC Code: 51111800
• PubChem Substance ID: 24900692
• NACRES: NA.32
• Biological source: synthetic (organic)
• Form: liquid

Properties

• biological source: synthetic (organic)
• Quality Level: 200
• sterility: non-sterile
• type: Grade VI (synthetic)
• form: liquid
• contains: 0.4% 4-chlorobutanol as preservative
• concentration: ~100 IU/mL in 0.9% NaCl
• pH: ~3.5
• UniProt accession no.: P01185
• shipped in: ambient

Description

Amino Acid Sequence

Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 [Disulfide Bridge: 1-6]

Application

[Arg⁸]-Vasopressin solution was used as an antigen for preparing preadsorbed antisera for immunocytochemistry. The product was used in L6 cell culture of the C5 subclone for differentiation studies.

Biochem/physiol Actions

Endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. Arg⁸-vasopressin is also a neurotransmitter in the central nervous system. It is implicated in a variety of physiological processes including diuresis, vasoregulation, and memory. Regulates water balance by antidiuretic action; contracts arterioles (vasopressor action).

Endogenous antidiuretic hormone in most mammalian species; neurotransmitter in the central nervous system implicated in a variety of physiological processes including diuresis, vasoregulation, and memory.

[Arg⁸]-Vasopressin solution also known as Antidiuretic hormone, Arginine vasopressin or beta-Hypophamine is a selective and potent vasopressor agent that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock. It stimulates three acid-base transporters and hence increases the capability of the cell to regulate pH.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup