202371

Poly(éthylène glycol)

average M_n 300, hydroxyl

• Synonyme(s) : PEG
• Formule linéaire : H(OCH₂CH₂)_nOH
• CAS Number: 25322-68-3
• Numéro MDL: MFCD00081839
• Code UNSPSC : 12352104
• ID de substance PubChem : 24852059
• Nomenclature NACRES : NA.23

Propriétés

• Product Name: Poly(éthylène glycol), average M_n 300
• Forme: viscous liquid
• Niveau de qualité: 200
• Poids mol.: M_n 285-315; average M_n 300
• Indice de réfraction: n20/D 1.463
• pH: 6-7 (23 °C, at 10 g/l)
• Viscosité: 5.8 cSt(210 °F)(lit.)
• Pf: −15-−8 °C (lit.)
• Densité: 1.125 g/mL at 25 °C
• Mw/Mn: 1.1 (typical)
• Extrémité Ω: hydroxyl
• Extrémité α: hydroxyl
• Chaîne SMILES: C(CO)O
• InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
• Clé InChI: LYCAIKOWRPUZTN-UHFFFAOYSA-N

Description

Description générale

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks, PEG can have high water content, forming "hydrogels". Hydrogel formation can be initiated by either crosslinking PEG by ionizing radiation or by covalent crosslinking of PEG macromers with reactive chain ends. PEG is a suitable material for biological applications because it does not trigger an immune response.

Application

• PEG modification increases thermostability and inhibitor resistance of Bst DNA polymerase.: This study demonstrates that polyethylene glycol (PEG) modification significantly enhances the thermostability and inhibitor resistance of Bst DNA polymerase, highlighting PEG′s potential in improving enzyme performance for biotechnological applications (Yang et al., 2024).


• Development of Lyophilized Eukaryotic Cell-Free Protein Expression System Based on Leishmania tarentolae.: The incorporation of PEG in the lyophilization process of a cell-free protein expression system demonstrates its role in enhancing the stability and efficiency of biotechnological workflows (Alfaro-Palma et al., 2024).


• A comprehensive review on singlet oxygen generation in nanomaterials and conjugated polymers for photodynamic therapy in the treatment of cancer.: This review highlights the application of PEGylated nanomaterials in photodynamic therapy, emphasizing its significance in improving biocompatibility and therapeutic efficacy in cancer treatments (Singh et al., 2024).

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 428.0 °F - closed cup
• Point d'éclair (°C): 220.00 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Gloves