Trimethoxymethylsilane (MTM) is an organosilicon compound widely used as a precursor for the preparation of silica-based materials, which finds the applications in various fields. Particularly in molecular assembly, linking nano building blocks, and selective synthesis oligosiloxane compounds. It can also be utilized as a crosslinker in the synthesis of polysiloxane polymers.

Trimethoxymethylsilane can be used:

• As a silica source for synthesizing polyethyleneimine-silica (PEI-silica) organic-inorganic hybrid particles.
• To transform hydrophilic ceramic surfaces to hydrophobic by modifying the -OH groups.
• To modify silica aerogels by inducing hydrophobicity and enhancing mechanical properties without affecting transparency.