About This Item
Qualité
certified reference material
Niveau de qualité
Forme
liquid
Caractéristiques
SNAP-N-SPIKE®, SNAP-N-SHOOT®
Conditionnement
ampule of 1 mL
Fabricant/nom de marque
Cerilliant®
drug control
Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)
Concentration
1.0 mg/mL in methanol
Technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
Application(s)
forensics and toxicology
Format
single component solution
Température de stockage
−20°C
Chaîne SMILES
CO[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]4Cc5ccc(O)c6O[C@@H]2[C@]3(CCN4CC7CC7)c56
InChI
1S/C29H41NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3/t20-,21-,24-,26+,27-,28+,29-/m1/s1
Clé InChI
RMRJXGBAOAMLHD-IHFGGWKQSA-N
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Description générale
Buprenorphine is a semi-synthetic opioid that shows partial agonistic activity towards the μ-opioid receptor and antagonistic activity towards the kappa opioid receptor. And even though it is similar to morphine, it is more potent than morphine. The drug is sold under numerous trade names such as Suboxone®, Subutex®, and Temgesic.
Application
- Multi-residue analysis of buprenorphine, norbuprenorphine, and naloxone in the fingernails and urine samples of previous heroin users under an opioid substitution therapy by solid-liquid or solid-phase extraction combined with liquid chromatography-mass spectrometry (LC-MS) for analysis
- Liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) based separation and determination of naloxone, buprenorphine, and norbuprenorphine in human plasma samples following their single-step liquid-liquid extraction (LLE)
- Development of nanocomposite rhodium nanoparticles-mesoporous carbon (RhNPs-MC) for their deposition on glassy carbon electrode (GCE) to compose an electrochemical sensor for the measurement of morphine and buprenorphine in pharmaceutical formulations and human serum samples using differential pulse voltammetry (DPV)
- Study of human blood plasma samples for the quantitative analysis of buprenorphine and naloxone by liquid chromatography (LC) coupled to high-resolution time-of-flight mass spectrometry (HR-Q-TOF-MS)
- Simultaneous determination of buprenorphine, norbuprenorphine, and their glucuronides from human urine samples by ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)
Caractéristiques et avantages
- Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
- Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
- Rigorously tested through real-time stability studies to ensure accuracy and shelf life
- Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
- Flame sealed under argon into ampoules for long-term shelf life
- Offered in a convenient, DEA-exempt format to improve laboratory efficiency
Informations légales
Mention d'avertissement
Danger
Mentions de danger
Conseils de prudence
Classification des risques
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
Organes cibles
Eyes,Central nervous system
Code de la classe de stockage
3 - Flammable liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
49.5 °F - closed cup
Point d'éclair (°C)
9.7 °C - closed cup
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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