SMRT is 1495 amino acids and contains an 8 amino acid sequence that is not present in SMRTe (SMRT-extended), which contains 2514 amino acids. SMRTe contains an N-terminal sequence spanning over 1,000 amino acids that is not present in SMRT, but that shows significant similarity with N-CoR. SMRTe expression is regulated during cell cycle progression, suggesting a role for SMRTe in the regulation of cycle-specific gene expression in diverse signaling pathways.

SMRT isoforms

GST fusion-protein corresponding to residues 1146-1349 of human SMRTe

Anti-SMRTe Antibody is a high quality Rabbit Polyclonal Antibody for the detection of SMRTe & has been validated in ChIP, ICC & WB.

Research Category
Protein Trafficking

Epigenetics & Nuclear Function

Research Sub Category
RNA Metabolism & Binding Proteins

Histones

RNA Binding Protein (RBP)

routinely evaluated by immunoblot on nuclear fraction from murine brain

270kDa, 180kDa and 80kDa

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%

Format: Purified

Protein A chromatography

Store at 2–8°C

Control
Mouse brain nuclear extract

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