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233483

Sigma-Aldrich

Coagulation Factor XIa, Human Plasma

Coagulation Factor XIa, Human Plasma, is a native coagulation factor XIa prepared from homogeneous Factor XI by activation with human Factor XIIa. Factor XIIa is removed after activation.

Synonyme(s) :

Coagulation Factor

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1 G
CA$480.00

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1 G
CA$480.00

About This Item

Code UNSPSC :
12352202
Nomenclature NACRES :
NA.25

CA$480.00

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Niveau de qualité

100

Forme

liquid

Fabricant/nom de marque

Calbiochem®

Conditions de stockage

OK to freeze
avoid repeated freeze/thaw cycles

Conditions d'expédition

wet ice

Température de stockage

−70°C

Description générale

Native coagulation factor XIa from human plasma prepared from homogeneous Factor XI by activation with human Factor XIIa. Factor XIIa is removed after activation. In vivo, Factor XI is activated to Factor XIa via Factor XIIa and High Molecular Weight Kininogen (Cat. No. 422686). Factor XIa activates Factor IX to Factor IXa in a reaction that does not require membrane surfaces.

Conditionnement

Please refer to vial label for lot-specific concentration.

Avertissement

Toxicity: Standard Handling (A)

Forme physique

In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.

Notes préparatoires

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Remarque sur l'analyse

homogeneous by SDS-PAGE

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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    Nine new (+/-)-8-alkyl-5,7-dihydroxy-4-(4-hydroxyphenyl)-3,4-dihydrocoumarins have been synthesized from 2,4,6-trimethoxybenzaldehyde via a short, efficient, and regioselective pathway, together with the unsubstituted analogue (+/-)-5,7-dihydroxy-4-(4-hydroxyphenyl)-3,4-dihydrocoumarin. The compounds were tested for estrogenic activity using a yeast-based estrogen screen. Weak estrogenicity was determined for seven members
    Fatemeh Oroojalian et al.
    Journal of controlled release : official journal of the Controlled Release Society, 288, 45-61 (2018-09-02)
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