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AB15452

Sigma-Aldrich

Anti-MAP2 Antibody

CHEMICON®, chicken polyclonal

Synonyme(s) :

Microtubule associated protein 2

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
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Product Name

Anti-MAP2 Antibody, Chemicon®, from chicken

Source biologique

chicken

Niveau de qualité

Forme d'anticorps

affinity purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

polyclonal

Produit purifié par

affinity chromatography

Espèces réactives

mouse

Fabricant/nom de marque

Chemicon®

Technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable

Comparer avec des articles similaires

Voir la comparaison complète

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1 of 4

Cet article
M3696MAB3418MAB364
biological source

chicken

biological source

rabbit

biological source

mouse

biological source

mouse

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

ascites fluid

Gene Information

mouse ... Map2(17756)

Gene Information

human ... MAP2(4133)
mouse ... Mtap2(17756)
rat ... Map2(25595)

Gene Information

chicken ... Map2(424001)
frog ... Map2(780043)
human ... MAP2(4133)
mouse ... Map2(17756), Map2(281294)
rat ... Map2(25595)

Gene Information

human ... MAP2(4133)

species reactivity

mouse

species reactivity

rat, mouse, human

species reactivity

bovine, mouse, rat, chicken, quail, Xenopus, human

species reactivity

bovine, human, quail, rat, chicken, mouse

UniProt accession no.

P11137

UniProt accession no.

P11137

UniProt accession no.

P11137

UniProt accession no.

P11137

Spécificité

MAP2 [Microtubule associated protein 2]
Other species have not yet been tested. It is expected that the antibody will also react with human due to immunogen sequence similarity.

Immunogène

Synthetic peptides corresponding to different regions of the human/mouse MAP2 protein.

Application

Anti-MAP2 Antibody detects level of MAP2 & has been published & validated for use in IC, IH.
Immunohistochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed tissue.

Immunocytochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed cells.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurofilament & Neuron Metabolism

Forme physique

Affinity purified chicken immunoglobulin. Two different antibodies were combined to make this product. Liquid in PBS, pH 7.2 with 0.02% sodium azide.
ImmunoAffinity Purified

Stockage et stabilité

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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    Yun Yang et al.
    Nature communications, 13(1), 159-159 (2022-01-12)
    Abnormalities in brain glucose metabolism and accumulation of abnormal protein deposits called plaques and tangles are neuropathological hallmarks of Alzheimer's disease (AD), but their relationship to disease pathogenesis and to each other remains unclear. Here we show that succinylation, a
    Protein Phosphatase 2a and glycogen synthase kinase 3 signaling modulate prepulse inhibition of the acoustic startle response by altering cortical M-Type potassium channel activity.
    Kapfhamer D, Berger KH, Hopf FW, Seif T, Kharazia V, Bonci A, Heberlein U
    The Journal of Neuroscience null
    Maria Vedunova et al.
    Frontiers in cellular neuroscience, 7, 149-149 (2013-09-26)
    The extracellular matrix (ECM) plays an important role in use-dependent synaptic plasticity. Hyaluronic acid (HA) is the backbone of the neural ECM, which has been shown to modulate α-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate (AMPA) receptor mobility, paired-pulse depression, L-type voltage-dependent Ca(2+) channel (L-VDCC) activity
    Shane Stegeman et al.
    PloS one, 8(7), e68287-e68287 (2013-07-19)
    The deubiquitylating enzyme Usp9x is highly expressed in the developing mouse brain, and increased Usp9x expression enhances the self-renewal of neural progenitors in vitro. USP9X is a candidate gene for human neurodevelopmental disorders, including lissencephaly, epilepsy and X-linked intellectual disability.
    Yuanchao Xue et al.
    Cell, 152(1-2), 82-96 (2013-01-15)
    The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the

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