Accéder au contenu
Merck

Principaux documents

Voir toute la documentation

Passer à

ABT69

Sigma-Aldrich

Anti-CCDC53 Antibody

from rabbit

Synonyme(s) :

coiled-coil domain containing 53, Coiled-coil domain-containing protein 53, WASH complex subunit CCDC53

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme

About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aider

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

human, rat, mouse

Technique(s)

western blot: suitable

Numéro d'accès NCBI

NP_057137

Numéro d'accès UniProt

Q9Y3C0

Conditions d'expédition

wet ice

Comparer avec des articles similaires

Voir la comparaison complète

Montrer les différences

1 of 4

Cet article
53557-U53559-U53560-U
Ascentis® Express 90 Å PFAS, 2.7 μm HPLC Column suitable for PFAS testing, column L × I.D. 25 cm × 3.0 mm

53570-U

Ascentis® Express 90 Å PFAS, 2.7 μm HPLC Column

Ascentis® Express 90 Å PFAS, 2.7 μm HPLC Column suitable for PFAS testing, column L × I.D. 5 cm × 2.1 mm

53557-U

Ascentis® Express 90 Å PFAS, 2.7 μm HPLC Column

Ascentis® Express 90 Å PFAS, 2.7 μm HPLC Column column L × I.D. 10 cm × 2.1 mm, suitable for PFAS testing

53559-U

Ascentis® Express 90 Å PFAS, 2.7 μm HPLC Column

Ascentis® Express 90 Å PFAS, 2.7 μm HPLC Column suitable for PFAS testing, column L × I.D. 15 cm × 2.1 mm

53560-U

Ascentis® Express 90 Å PFAS, 2.7 μm HPLC Column

particle size

2.7 μm

particle size

2.7 μm

particle size

2.7 μm

particle size

2.7 μm

separation technique

reversed phase

separation technique

reversed phase

separation technique

reversed phase

separation technique

reversed phase

matrix active group

C18, extensively endcapped octadecylsilane (ODS) bonding phase

matrix active group

C18, extensively endcapped octadecylsilane (ODS) bonding phase

matrix active group

C18, extensively endcapped octadecylsilane (ODS) bonding phase

matrix active group

C18, extensively endcapped octadecylsilane (ODS) bonding phase

agency

suitable for ASTM® 7968, suitable for DIN 38407-42, suitable for EPA 537.1, suitable for EPA ACB B21-02, suitable for EPA OTM-45, suitable for ISO 21675 2019, suitable for ISO/CEN 15968-2010, suitable for ASTM® 7979, suitable for EPA 8327, suitable for GB 5009.253-2016, suitable for USP L1, suitable for EPA 533, suitable for ISO 25101, suitable for EPA ACB B23-05b

agency

suitable for ASTM® 7968, suitable for ASTM® 7979, suitable for DIN 38407-42, suitable for EPA 533, suitable for EPA 537.1, suitable for EPA 8327, suitable for EPA ACB B21-02, suitable for EPA ACB B23-05b, suitable for EPA OTM-45, suitable for GB 5009.253-2016, suitable for ISO 21675 2019, suitable for ISO 25101, suitable for ISO/CEN 15968-2010, suitable for USP L1

agency

suitable for ASTM® 7968, suitable for ASTM® 7979, suitable for DIN 38407-42, suitable for EPA 533, suitable for EPA 537.1, suitable for EPA 8327, suitable for EPA ACB B21-02, suitable for EPA ACB B23-05b, suitable for EPA OTM-45, suitable for GB 5009.253-2016, suitable for ISO 21675 2019, suitable for ISO 25101, suitable for ISO/CEN 15968-2010, suitable for USP L1

agency

suitable for ASTM® 7968, suitable for ASTM® 7979, suitable for DIN 38407-42, suitable for EPA 533, suitable for EPA 537.1, suitable for EPA 8327, suitable for EPA ACB B21-02, suitable for EPA ACB B23-05b, suitable for EPA OTM-45, suitable for GB 31604.35-2016, suitable for GB 5009.253-2016, suitable for ISO 21675 2019, suitable for ISO 25101, suitable for ISO/CEN 15968-2010, suitable for USP L1

technique(s)

HPLC: suitable, LC/MS: suitable

technique(s)

HPLC: suitable, LC/MS: suitable, UHPLC-MS: suitable, UHPLC: suitable

technique(s)

HPLC: suitable, LC/MS: suitable, UHPLC-MS: suitable, UHPLC: suitable

technique(s)

HPLC: suitable, LC/MS: suitable, UHPLC-MS: suitable, UHPLC: suitable

pore size

90 Å pore size

pore size

90 Å pore size

pore size

90 Å pore size

pore size

90 Å pore size

Description générale

Coiled-coil domain-containing protein 53 (CCDC53) is one of several components comprising the WASH complex, a complex localized to endosomal surfaces that functions to upregulate actin polymerization through the recruiting and activation of Arp2/3 complex. WASH is a critical component in the fission of tubules (transport intermediates involved in the distribution of endosomes). The WASH complex is composed of CCDC53, F-actin-capping protein subunits alpha and beta, WASH, FAM21, KIAA1033, and KIAA196.

Immunogène

GST-tagged recombinant protein corresponding to human CCDC53.

Application

Research Category
Cell Structure
Research Sub Category
Cytoskeletal Signaling
This Anti-CCDC53 Antibody is validated for use in WB for the detection of CCDC53.
Western Blot Analysis: 2.5 µg/mL from a representative lot detected CCDC53 in 10 µg of mouse brain and PC12 cell lysate.

Qualité

Evaluated by Western Blot in HepG2 cell lysate.

Western Blot Analysis: 2.5 µg/mL of this antibody detected CCDC53 in 10 µg of HepG2 cell lysate.

Description de la cible

~28 kDa observed

Forme physique

Format: Purified
Protein G Purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
HepG2 cell lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Vous ne trouvez pas le bon produit ?  

Essayez notre Outil de sélection de produits.

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Hongmei Li et al.
Nature cell biology, 15(7), 773-785 (2013-06-25)
Following exocytosis, the rate of recovery of neurotransmitter release is determined by vesicle retrieval from the plasma membrane and by recruitment of vesicles from reserve pools within the synapse, which is dependent on mitochondrial ATP. The anti-apoptotic Bcl-2 family protein
Hala Guedouari et al.
Biochimica et biophysica acta. Molecular cell research, 1864(1), 169-176 (2017-03-28)
During starvation, intra-mitochondrial sirtuins, NAD+ sensitive deacylating enzymes that modulate metabolic homeostasis and survival, directly adjust mitochondrial function to nutrient availability; concomitantly, mitochondria elongate to escape autophagic degradation. However, whether sirtuins also impinge on mitochondrial dynamics is still uncharacterized. Here
Shilpa Gandre-Babbe et al.
Molecular biology of the cell, 19(6), 2402-2412 (2008-03-21)
Few components of the mitochondrial fission machinery are known, even though mitochondrial fission is a complex process of vital importance for cell growth and survival. Here, we describe a novel protein that controls mitochondrial fission. This protein was identified in
Sebastian Carsten Johannes Helle et al.
eLife, 6 (2017-11-10)
Eukaryotic cells are densely packed with macromolecular complexes and intertwining organelles, continually transported and reshaped. Intriguingly, organelles avoid clashing and entangling with each other in such limited space. Mitochondria form extensive networks constantly remodeled by fission and fusion. Here, we
Carmela Guido et al.
Oncotarget, 3(8), 798-810 (2012-08-11)
Recent studies have suggested that cancer cells behave as metabolic parasites, by inducing oxidative stress in adjacent normal fibroblasts. More specifically, oncogenic mutations in cancer cells lead to ROS production and the "secretion" of hydrogen peroxide species. Oxidative stress in
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique