125660

Leucomalachite Green

powder

• Synonyme(s) : 4,4′-Benzylidenebis(N,N-dimethylaniline)
• Formule linéaire : C₆H₅CH[C₆H₄N(CH₃)₂]₂
• CAS Number: 129-73-7
• Poids moléculaire : 330.47
• Beilstein: 2140506
• Numéro CE : 204-961-9
• Numéro MDL: MFCD00008315
• Code UNSPSC : 12171500
• ID de substance PubChem : 24847677
• Nomenclature NACRES : NA.47

Propriétés

• Forme: powder
• Niveau de qualité: 100
• Technique(s): microbe id | staining: suitable
• Pf: 100-102 °C (lit.)
• λmax: 623 nm
• Application(s): diagnostic assay manufacturing; hematology; histology
• Température de stockage: room temp
• Chaîne SMILES: CN(C)c1ccc(cc1)C(c2ccccc2)c3ccc(cc3)N(C)C
• InChI: 1S/C23H26N2/c1-24(2)21-14-10-19(11-15-21)23(18-8-6-5-7-9-18)20-12-16-22(17-13-20)25(3)4/h5-17,23H,1-4H3
• Clé InChI: WZKXBGJNNCGHIC-UHFFFAOYSA-N

Description

Application

Leucomalachite green has been used as a reagent in presumptive tests which are used to detect invisible blood stains.[1][2]

Actions biochimiques/physiologiques

Leucomalachite green (LMG) is a chief metabolite of malachite green, a triphenylmethane dye that has been used generally as an antifungal drug in the fish industry. DNA adducts formed in livers of rats fed with leucomalachite green have been observed with little mutagenic or carcinogenic effect.[3] LMG is one of the most commonly used reagents for presumptive blood test. It gives a characteristic green color in the presence of blood. LMG destroys DNA in the blood, therefore, the chances of DNA recovery and amplification is reduced or eliminated.[4]

Informations sur la sécurité

• Pictogrammes: GHS08,GHS07,GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H302,H341,H351,H410
• Conseils de prudence: P202 - P264 - P273 - P280 - P301 + P312 - P308 + P313
• Classification des risques: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Muta. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves