2106

Héparine sodium salt from porcine intestinal mucosa

endotoxin, free

• CAS Number: 9041-08-1
• Numéro MDL: MFCD00081689
• Code UNSPSC : 12352201
• Nomenclature NACRES : NA.21

Propriétés

• Source biologique: Porcine intestinal mucosa
• Niveau de qualité: 200
• Forme: powder
• Utilisation: sufficient for 5 mL blood anticoagulant
• Conditionnement: preweighed vial of 300 USP units
• Impuretés: endotoxin, free
• Couleur: beige
• Solubilité: water: soluble 50 g/L; acetone: insoluble; alcohol: insoluble; benzene: insoluble; chloroform: insoluble; diethyl ether: insoluble
• Compatibilité: for use with E-Toxate^™
• Température de stockage: room temp
• Chaîne SMILES: [Na+].[S](=O)(=O)(NC1C(OC(C(C1O[S](=O)(=O)O)OC4OC(C(C(C4O[S](=O)(=O)O)O)O)C(=O)O)CO)OC2C(OC(C(C2O)O[S](=O)(=O)O)OC3C(OC(C(C3O)NC(=O)C)O)CO[S](=O)(=O)O)C(=O)O)O
• InChI: 1S/C26H42N2O37S5.Na/c1-4(30)27-7-9(31)13(6(56-23(7)39)3-55-67(43,44)45)58-26-19(65-70(52,53)54)12(34)16(20(62-26)22(37)38)60-24-8(28-66(40,41)42)15(63-68(46,47)48)14(5(2-29)57-24)59-25-18(64-69(49,50)51)11(33)10(32)17(61-25)21(35)36;/h5-20,23-26,28-29,31-
• Clé InChI: JRTRSJGZMRQDHI-UHFFFAOYSA-N

Description

Application

Heparin sodium salt from porcine intestinal mucosa has been used as a M199 medium supplement used for maintaining human umbilical vein endothelial cells.

Actions biochimiques/physiologiques

Heparin sodium salt is the salt form of heparinic acid and is a polymer classified as a mucopolysaccharide or a glycosoaminoglycan. It is an anticoagulant that produces its major anticoagulant effect by activating antithrombin. Heparin binds to antithrombin III, a naturally occurring plasma protease inhibitor and accelerates significantly the rate at which antithrombin III (AT-III) inhibits coagulation proteases (factor Xa and thrombin). Additionally, it also facilitates the stabilization and regulation of tryptase as an enzymatically active tetramer.

Attention

Not for injection.

Autres remarques

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Informations légales

E-Toxate is a trademark of Sigma-Aldrich Co. LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)