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PHR2226

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Duloxetine Related Compound A

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

(R)-Duloxetine hydrochloride, (R)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride, (R)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride

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About This Item

Formule empirique (notation de Hill) :
C18H19NOS · HCl
CAS Number:
Poids moléculaire :
333.88
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24
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Qualité

certified reference material
pharmaceutical secondary standard

Niveau de qualité

Agence

traceable to Ph. Eur. Y0001455
traceable to USP 1229828

Famille d'API

duloxetine, duloxetine

Forme

powder

CofA (certificat d'analyse)

current certificate can be downloaded

Conditionnement

pkg of 25 mg

Application(s)

pharmaceutical

Température de stockage

2-8°C

Chaîne SMILES 

[s]1c(ccc1)[C@H](Oc2c3c(ccc2)cccc3)CCNC.Cl

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Cet article
8.20565F3800F7601
2-Fluoroaniline ≥99%

F3401

2-Fluoroaniline

4-Fluoroaniline 99%

F3800

4-Fluoroaniline

assay

≥99%

assay

≥98.0% (GC)

assay

99%

assay

98%

Quality Level

100

Quality Level

200

Quality Level

-

Quality Level

100

bp

182-183 °C (lit.)

bp

171-173 °C/1013 hPa

bp

187 °C/767 mmHg (lit.)

bp

86 °C/40 mmHg (lit.)

density

1.151 g/mL at 25 °C (lit.)

density

1.15 g/cm3 at 20 °C

density

1.173 g/mL at 25 °C (lit.)

density

1.216 g/mL at 25 °C (lit.)

refractive index

n20/D 1.544 (lit.)

refractive index

-

refractive index

n20/D 1.539 (lit.)

refractive index

n20/D 1.514 (lit.)

mp

−29 °C (lit.)

mp

-29 °C

mp

-

mp

-

Description générale

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAC3404 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Qing-Lei Zeng et al.
Molecules and cells, 37(1), 66-73 (2014-02-21)
Myeloid-derived suppressor cells (MDSCs) play an important role in impairing the function of T cells. We characterized MDSCs in two chronic hepatitis C (CHC) cohorts: a cross-sectional group that included 61 treatment-naive patients with CHC, 14 rapid virologic response (RVR)
Wei Xia Ang et al.
Oncotarget, 8(8), 13545-13559 (2017-01-16)
The epithelial cell adhesion molecule (EpCAM) is overexpressed in a wide variety of tumor types, including peritoneal carcinomatosis (PC) from gastrointestinal and gynecological malignancies. To develop a chimeric antigen receptor T (CART) cell therapy approach to treat patients with end-stage
Seamus Grundy et al.
PloS one, 8(8), e71629-e71629 (2013-08-27)
CD8 cells may contribute towards an autoimmune process in COPD. Down regulation of T cell receptor (TCR) signalling molecules occurs in autoimmune diseases with consequent T cell dysfunction. We hypothesise that TCR signalling is abnormal in COPD pulmonary CD8 cells.
Tsutomu Takeuchi et al.
Rheumatology (Oxford, England), 52(9), 1551-1555 (2013-03-26)
SLE is associated with a deficiency in cluster of differentiation 247 (CD247, also known as CD3 zeta chain), a component of the T-cell receptor (TCR)-CD3 complex. A comprehensive analysis showed that in more than half of SLE patients tested CD247
María Teruel et al.
PloS one, 8(7), e68295-e68295 (2013-07-19)
Given the role of CD247 in the response of the T cells, its entailment in autoimmune diseases and in order to better clarify the role of this gene in RA susceptibility, we aimed to analyze CD247 gene variants previously associated

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