46121

Resorufin ethyl ether

suitable for fluorescence, ≥95% (UV)

• Synonyme(s) : 7-Ethoxy-3H-phenoxazin-3-one, Ethoxyresorufin, O⁷-Ethylresorufin
• Formule empirique (notation de Hill) : C₁₄H₁₁NO₃
• CAS Number: 5725-91-7
• Poids moléculaire : 241.24
• Beilstein: 225973
• Numéro MDL: MFCD00037661
• Code UNSPSC : 12161501
• ID de substance PubChem : 329757074
• Nomenclature NACRES : NA.32

Propriétés

• Niveau de qualité: 100
• Essai: ≥95% (UV)
• Forme: solid
• Pf: 223-225 °C (lit.)
• Solubilité: DMF: soluble; DMSO: soluble; alcohols: soluble
• Fluorescence: λ_ex 464 nm; λ_em 540 nm in methanol(lit.); λ_ex 571 nm; λ_em 585 nm in dealkylase(lit.)
• Adéquation: suitable for fluorescence
• Température de stockage: 2-8°C
• Chaîne SMILES: CCOc1ccc2N=C3C=CC(=O)C=C3Oc2c1.Fc4c(F)c(F)c(OC(=O)CNC(=O)OCC5c6ccccc6-c7ccccc57)c(F)c4F
• InChI: 1S/C23H14F5NO4.C14H11NO3/c24-17-18(25)20(27)22(21(28)19(17)26)33-16(30)9-29-23(31)32-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15;1-2-17-10-4-6-12-14(8-10)18-13-7-9(16)3-5-11(13)15-12/h1-8,15H,9-10H2,(H,29,31);3-8H,2H2,1H3
• Clé InChI: ZOSYTBPPLWBBKM-UHFFFAOYSA-N

Description

Application

7-Ethoxyresorufin (7-ER) is a substrate used in environmental toxicology studies to monitor ethoxyresorufin-O-deethylase catalytic activity in the EROD assay. The EROD assay monitors the induction of the xenobiotic-metabolizing enzyme cytochrome P-450 (CYP) 1A1 and is a widely used biomarker for exposure of wildlife to substances that bind the aryl hydrocarbon (Ah) receptor. It provides evidence of receptor-mediated induction of cytochrome P450-dependant monooxygenases (the CYP1A subfamily specifically) by xenobiotic chemicals.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Autres remarques

Dealkylase substrate for the microfluorimetric analysis of microsomal cytochrome P-450

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)