58030

Iodonitrotetrazolium chloride

BioReagent, ≥97.0% (calc. on dry substance, NT)

• Synonyme(s) : 2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride, p-Iodonitrotetrazolium Violet, INT
• Formule empirique (notation de Hill) : C₁₉H₁₃ClIN₅O₂
• CAS Number: 146-68-9
• Poids moléculaire : 505.70
• Beilstein: 4093224
• Numéro CE : 205-676-2
• Numéro MDL: MFCD00011961
• Code UNSPSC : 12352102
• ID de substance PubChem : 57651636
• Nomenclature NACRES : NA.25

Propriétés

• Gamme de produits: BioReagent
• Niveau de qualité: 200
• Essai: ≥97.0% (calc. on dry substance, NT)
• Pf: 240 °C (dec.) (lit.); ~245 °C (dec.)
• Solubilité: methanol: water (1:1): 50 mg/mL, very faintly turbid, very deep yellow (hot)
• Application(s): histology
• Chaîne SMILES: [Cl-].[O-][N+](=O)c1ccc(cc1)-[n+]2nc(nn2-c3ccc(I)cc3)-c4ccccc4
• InChI: 1S/C19H13IN5O2.ClH/c20-15-6-8-16(9-7-15)23-21-19(14-4-2-1-3-5-14)22-24(23)17-10-12-18(13-11-17)25(26)27;/h1-13H;1H/q+1;/p-1
• Clé InChI: JORABGDXCIBAFL-UHFFFAOYSA-M

Description

Application

Electron acceptor for the colorimetric assay of various dehydrogenases

Iodonitrotetrazolium (INT) is a tetrazolium dye precursor that forms a purple formazan dye on reduction and has been used in a variety of applications. It is considered to have higher reactivity than some tetrazolium compounds, at least with respect to succinate dehydrogenase, with optimal results obtained using a concentration of 0.8 mM INT. INT is used as an electron acceptor for the colorimetric assays of: lactate dehydrogenase, xanthine dehydrogenase, lactyl-CoA dehydrogenase, succinate dehydrogenase, BBM II ketolisomerase, histidinol dehydrogenase and diverse other hydrolases.

Informations sur la sécurité

• Pictogrammes: GHS02,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H228,H335
• Conseils de prudence: P210 - P240 - P241 - P261 - P271 - P280
• Classification des risques: Flam. Sol. 1 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 4.1B - Flammable solid hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)