I8907

Interferon β from rat

≥95%, recombinant, expressed in CHO cells, lyophilized powder, suitable for cell culture

• Synonyme(s) : IFN-β
• Numéro MDL: MFCD04040885
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: rat
• Niveau de qualité: 200
• Produit recombinant: expressed in CHO cells
• Essai: ≥95%
• Forme: lyophilized powder
• Poids mol.: ~20 kDa
• Conditionnement: pkg of 1 vial
• Concentration: ≥100000 units/mL
• Technique(s): cell culture | mammalian: suitable
• Numéro d'accès UniProt: P70499

Description

Actions biochimiques/physiologiques

Cytokine with anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities.

Interferon β belongs to the type 1 interferon family pf proteins. It is also needed for the inhibition of tumor cell growth via cell death, S-phase increase and mediating differentiation. It is also important for bone homeostasis.

Forme physique

Lyophilized from phosphate buffered saline (PBS) containing 125 mM trehalose.

Remarque sur l'analyse

The biological activity is determined in the cytopathic effect inhibition assay using rat epithelial-like (RATEC) cells with vesicular stomatitis virus (VSV). The cytopathic effect of 50% is produced with approximately 1 unit/ml interferon. Since there is no international rat interferon β standard, units are determined with respect to the NIH international standard reference for mouse interferon α/β.

Informations sur la sécurité

• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)