S5261

Sodium selenite

BioReagent, suitable for cell culture, ≥98%

• Synonyme(s) : Selenious acid, Sodium salt
• Formule linéaire : Na₂SeO₃
• CAS Number: 10102-18-8
• Poids moléculaire : 172.94
• Numéro CE : 233-267-9
• Numéro MDL: MFCD00003489
• Code UNSPSC : 12352205
• ID de substance PubChem : 24899643
• Nomenclature NACRES : NA.75

Propriétés

• Source biologique: synthetic (inorganic)
• Gamme de produits: BioReagent
• Essai: ≥98%
• Forme: powder
• Technique(s): cell culture | mammalian: suitable
• Pf: >350 °C (lit.)
• Solubilité: water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
• Chaîne SMILES: [Na+].[Na+].[O-][Se]([O-])=O
• InChI: 1S/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2
• Clé InChI: BVTBRVFYZUCAKH-UHFFFAOYSA-L

Description

Application

Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.

This product is cell culture tested (0.005 mg/L) and is appropriate for use in cell culture applications.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H300 + H330,H315,H317,H319,H411
• Conseils de prudence: P260 - P273 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
• Risques supp: EUH031
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges