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SAB4502966

Sigma-Aldrich

Anti-Tyrosine Hydroxylase Antibody

rabbit polyclonal

Synonyme(s) :

TH isoform 3, TH isoform a, TH-4, TY3H, TYH

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1 EA
MYR 2,314.20

About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

MYR 2,314.20


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Product Name

Anti-Tyrosine Hydroxylase, N-Terminal antibody produced in rabbit, affinity isolated antibody

Source biologique

rabbit

Niveau de qualité

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Poids mol.

antigen 58 kDa

Espèces réactives

rat, mouse, human

Catégories apparentées

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Cet article
SAB4300674T8700AB5986P
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

100

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity purified immunoglobulin

technique(s)

ELISA: 1:20000, immunohistochemistry: 1:50-1:100, immunofluorescence: 1:100-1:500, western blot: 1:500-1:1000

technique(s)

western blot: 1:500-1:1000

technique(s)

immunohistochemistry (frozen sections): 1:1,000, indirect immunofluorescence: 1:1,000, western blot: 1:1,000 using rat brain lysates of PC-12 cells stimulated by okadaic acid

technique(s)

immunohistochemistry: suitable

species reactivity

rat, mouse, human

species reactivity

rat, human, mouse

species reactivity

mammals

species reactivity

rat

Description générale

Anti-Tyrosine Hydroxylase Antibody detects endogenous levels of total Tyrosine Hydroxylase protein.
The TH (tyrosine Hydroxylase) gene codes for a homotetramer that contains catalytic, regulatory, and tetramerization domains in each of its subunit.

Immunogène

The antiserum was produced against synthesized peptide derived from human Tyrosine Hydroxylase.

Immunogen Range: 41-90

Application

Anti-Tyrosine Hydroxylase, N-Terminal antibody produced in rabbit has ben used in immunohistochemistry.

Actions biochimiques/physiologiques

The conversion of l-tyrosine into l-DOPA (L-3,4-dihydroxyphenylalanine) is catalyzed by tyrosine hydroxylase (TH), which is the rate-limiting step in the in the synthesis of catecholamines such as dopamine and also other necessary hormones and neuromodulators. The TH enzyme deficiency results in low levels of dopamine, which is characterised in Parkinson′s disease.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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