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About This Item
Linear Formula:
[C3H4O2]x[C2H2O2]y
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
Quality Level
form
amorphous
feed ratio
lactide:glycolide 85:15
mol wt
Mw 50,000-75,000
degradation timeframe
<6 months
viscosity
0.55-0.75 dL/g, 0.1 % (w/v) in chloroform(25 °C)
transition temp
Tg 45-50 °C
solubility
ethyl acetate, chloroform, acetone and THF: soluble
storage temp.
2-8°C
SMILES string
OCC(O)=O.CC(O)C(O)=O
InChI
1S/C3H6O3.C2H4O3/c1-2(4)3(5)6;3-1-2(4)5/h2,4H,1H3,(H,5,6);3H,1H2,(H,4,5)
InChI key
XBBVURRQGJPTHH-UHFFFAOYSA-N
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General description
Characteristic properties of ester terminated poly(D,L-lactide-co-glycolide) (PLGA) are in vivo biodegradability, tunable drug release profile and very high encapsulation capacity.
Application
PLGA polymers find uses in the production of biodegradable medical sutures and for controlled drug release. PLGA microspheres have been reported for use in controlled release of human growth hormone. Thin membranes of blended polymers constituting of PLGA/polycaprolactone/β-tricalcium phosphate have been used in guided bone regeneration.
Features and Benefits
Controlled release of bioactive agents, sutures and bioabsorbable implantable devices.
Physical form
Biocompatible, biodegradable polymer.
Legal Information
Lactel is a registered trademark of Evonik Corp
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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