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901332

Sigma-Aldrich

Polyester bis-MPA dendron 8 NHBoc, 1 azide (core)

generation 3

Synonym(s):

Bis-MPA dendron, PFd-G3-Azide-NH-BOC

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1 L
CA$173.00

About This Item

Empirical Formula (Hill Notation):
C105H173N11O46
Molecular Weight:
2325.54
UNSPSC Code:
12352125
NACRES:
NA.23

CA$173.00


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description

8 NHBoc, 1 azide (core)

Quality Level

form

solid

mol wt

generation 3

no. Surface Groups

8

color

white to off-white

functional group

azide (core)

storage temp.

−20°C

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This Item
901297901311
form

solid

form

solid

form

solid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

description

8 NHBoc, 1 azide (core)

description

4 NHBoc, 1 azide (core)

description

2 NHBoc, 1 azide (core)

mol wt

generation 3

mol wt

generation 2

mol wt

generation 1

no. Surface Groups

8

no. Surface Groups

4

no. Surface Groups

2

color

white to off-white

color

white to off-white

color

white to off-white

General description

  • Polymer architecture: Dendron
  • End Group Functionality: Boc-protected amine
  • Boc : tert-Butyloxycarbonyl
  • Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid.

Application

Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. After Boc deprotection, amine-functionalized dendrons can be readily used in EDC or DCC coupling reactions with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical applications. Additionally, the azide-core can be readily conjugated using either copper(I)-catalysed alkyne-azide cycloaddition (CuAAC) or strain-promoted alkyne-azide cycloaddition (SPAAC).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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