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939390

Sigma-Aldrich

Cobalt(II) fluoride tetrahydrate

greener alternative

99.9% trace metals basis

Synonym(s):

Cobalt difluoride hydrate, Cobaltous fluoride tetrahydrate, Difluorocobalt hydrate

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1 VIAL
CA$1,100.00

About This Item

Linear Formula:
CoF2 · 4H2O
CAS Number:
Molecular Weight:
168.99
MDL number:
UNSPSC Code:
12352200
Form:
powder or crystals
Solubility:
water: solubleslightly

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type

(High purity Salts)

Quality Level

Assay

98-102% (complexometric)
99.9% trace metals basis

form

powder or crystals

greener alternative product characteristics

Catalysis
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impurities

≤1500 ppm (trace metals analysis)

color

faint red to dark red/pink

mp

200 °C

solubility

water: solubleslightly

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1 of 4

This Item
P6993C4237M1941
specific activity

~2.0 U/vial

specific activity

≥1500 units/mg protein

specific activity

≥15,000 units/mg protein

specific activity

≥1000 units/mg protein

biological source

bovine kidney

biological source

bovine

biological source

-

biological source

bovine kidney

form

buffered aqueous glycerol solution

form

solution

form

buffered aqueous glycerol solution

form

solution

mol wt

dimer 101 kDa (65 kDa and 36 kDa)

mol wt

192 kDa

mol wt

45 kDa

mol wt

40 kDa

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

General description

Cobalt(II) fluoride tetrahydrate is a reddish crystalline solid with slight solubility in water. It serves as a source of cobalt for oxygen-sensitive applications. Additionally, it is employed as a catalyst biaryl cross-coupling reactions.
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Application

Cobalt(II) fluoride tetrahydrate is used as a starting material to synthesize 2-dimensional cobalt-fluoride-oxide as an oxygen evolution electrocatalysts using a rapid thermal annealing (RTA) method. In this process, the cobalt(II) fluoride tetrahydrate is placed in an alumina furnace at 400°C. After annealing for 20 minutes in air, the alumina crucible is removed and allowed to cool naturally to room temperature. The resulting products are then rinsed multiple times in deionized water and ethanol to remove any soluble impurities. Finally, the product is dried thoroughly in a vacuum oven at 60°C to obtain the 2D nanosheets sample. [1] Furthermore, when combined with N-Heterocyclic Carbenes, Cobalt(II) fluoride tetrahydrate has been found to be highly effective as a catalyst for cross-coupling reactions between aryl Grignard reagents and aryl as well as heteroaryl halides. This reaction results in the formation of unsymmetrical biaryls.[2]

Pictograms

Skull and crossbonesCorrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Protein Phosphatase 2A is a specific protamine-kinase-inactivating phosphatase.
Amick, G.D, et al.
The Biochemical Journal, (Pt 3), 1019-1022 (1992)
G D Amick et al.
Archives of biochemistry and biophysics, 297(1), 80-85 (1992-08-15)
About an eightfold increase in protamine kinase activity was detected following extraction of highly purified microsomes from bovine kidney with 1% Triton X-100. Relative to the soluble fraction, the microsomes contained about 30% protamine kinase activity. The microsomal protamine kinase
H R Matthews et al.
FEBS letters, 364(1), 51-54 (1995-05-01)
Whole cell extracts from rat liver or spinach leaves contain divalent ion-independent protein histidine phosphatase activity due to phosphatases of the PP1/PP2A family. In the rat liver extract, almost all the activity was found in the PP1, PP2A1 and PP2A2
M Li et al.
Biochemistry, 34(6), 1988-1996 (1995-02-14)
Two heat-stable protein inhibitors of protein phosphatase 2A (PP2A), tentatively designated I1PP2A and I2PP2A, have been purified to apparent homogeneity from extracts of bovine kidney. The purified preparations of I1PP2A exhibited an apparent M(r) approximately 30,000 and 250,000 as determined
A Hiraga et al.
The Biochemical journal, 346 Pt 2, 433-439 (2000-03-24)
Protein phosphatase (PP) 2A1, a trimer composed of A-, B- and C-subunits in the PP2A family, has been regarded as a principal form localizing at microtubules (MT), but PP2A2, the dimer of A- and C-subunits, has not. Substantiating the claim

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