860527P

C24 Ceramide-1-Phosphate (d18:1/24:0)

Avanti Research^™ - A Croda Brand 860527P, powder

• Synonym(s): N-lignoceroyl-ceramide-1-phosphate (ammonium salt)
• Empirical Formula (Hill Notation): C₄₂H₈₇N₂O₆P
• CAS Number: 1246303-20-7
• Molecular Weight: 747.12
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 1 mg (860527P-1mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 860527P
• lipid type: sphingolipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)COP([O-])(O)=O.[NH4+]
• InChI key: JGGZHGYBRJNAOW-FHPBFELKSA-N

Description

General description

Ceramide 1-phosphate (C1P) is a sphingolipid analog of phosphatidate.

Application

C24 Ceramide-1-Phosphate (d18:1/24:0) or N-lignoceroyl-ceramide-1-phosphate (ammonium salt) has been used as a standard to quantify ceramide content in muscle tissue samples using high-performance liquid chromatography/tandem mass spectrometry (LC/MS2).

Biochem/physiol Actions

Ceramide 1-phosphate (C1P) is a mitogenic agent, which has antiapoptotic and prosurvival activities. It negatively regulates tumor necrosis factor-α (TNFα) production stimulated by lipopolysaccharide. C1P also mediates inflammatory response and aids in phagocytosis. It is considered as a second lipid messenger of agonist-stimulated sphingomyelin metabolism.

Packaging

5 mL Amber Glass Screw Cap Vial (860527P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids