32810

1,4-Diaminobutane dihydrochloride

purum, ≥99.0% (AT)

• Synonym(s): Putrescine dihydrochloride, 1,4-Butanediamine dihydrochloride, 1,4-Diaminobutane dihydrochloride, Tetramethylenediamine dihydrochloride
• Linear Formula: NH₂(CH₂)₄NH₂ · 2HCl
• CAS Number: 333-93-7
• Molecular Weight: 161.07
• Beilstein: 3906680
• EC Number: 206-375-9
• MDL number: MFCD00012526
• UNSPSC Code: 12352116
• PubChem Substance ID: 329754336
• NACRES: NA.22

Properties

• grade: purum
• Quality Level: 400
• Assay: ≥99.0% (AT)
• form: powder
• mp: 280 °C (dec.) (lit.)
• solubility: water: soluble 1 g/10 mL, clear, colorless
• SMILES string: Cl[H].Cl[H].NCCCCN
• InChI: 1S/C4H12N2.2ClH/c5-3-1-2-4-6;;/h1-6H2;2*1H
• InChI key: XXWCODXIQWIHQN-UHFFFAOYSA-N

Description

Application

• Nanocomposite PLA/C20A nanoclay by ultrasound-assisted melt extrusion for adsorption of uremic toxins and methylene blue dye: This study explored the modification of nanoclay with 1,4-diaminobutane dihydrochloride for adsorptive applications, showing enhanced performance in toxin removal (Andrade-Guel et al., 2021).
• The Total Synthesis of Spermine Alkaloid Kukoamine Bimesylate: This paper details the synthetic route of spermine alkaloid derivatives using 1,4-diaminobutane dihydrochloride, highlighting methods applicable in medicinal chemistry (Dong, 2018).

Biochem/physiol Actions

Binds to the polyamine modulatory site of the NMDA receptor and potentiates NMDA-induced currents; precursor of spermidine.

Binds to the polyamine modulatory site of the NMDA receptor; potentiates NMDA-induced currents.

Safety Information

• Pictograms: GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H302,H311,H314,H330
• Precautionary Statements: P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 1
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves