439142

Chloroform

suitable for HPLC, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

• Synonym(s): Methylidyne trichloride, Trichloromethane
• Empirical Formula (Hill Notation): CHCl₃
• CAS Number: 67-66-3
• Molecular Weight: 119.38
• Beilstein: 1731042
• MDL number: MFCD00000826
• UNSPSC Code: 12190000
• PubChem Substance ID: 24867327
• Grade: HPLC grade
• Assay: ≥99.8%
• Technique(s): HPLC: suitable
• Application(s): food and beverages
• Bp: 60.5-61.5 °C (lit.)
• Vapor pressure: 160 mmHg ( 20 °C)

Properties

• grade: HPLC grade
• Quality Level: 100
• vapor density: 4.1 (vs air)
• vapor pressure: 160 mmHg ( 20 °C)
• Assay: ≥99.8%
• form: liquid
• contains: 0.5-1.0% ethanol as stabilizer
• packaging: PVC-coated bottle of 4, 4x4 L
• technique(s): HPLC: suitable
• impurities: <0.01% water

Description

General description

Chloroform is a colorless, volatile chlorinated organic solvent whose vapors have a narcotic effect.[1] It is susceptible to degradation with time, which can be suppressed by adding ethanol as a stabilizer. Since ethanol is added in higher concentration it leads to increase in polarity which may have a potential influence on some of the applications. Reports suggest that chloroform stabilized with ethanol reduces chances on creating artifacts during the chromatographic separation after extraction of anthracyclines from biological matrices.[2]

Application

Chloroform was used as an organic phase in the methylene blue (MB) two-phase titration process for estimating the cationic surfactant content in high salinity brine.[3]
It may be used as:

• Solvent for electropolymerization.[4]
• Solvent for recrystallization.[5]
• Extractant in solvent extraction process.[6]

Packaging

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Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372
• Precautionary Statements: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Target Organs: Central nervous system, Liver,Kidney
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point(F): does not flash
• Flash Point(C): does not flash