I2512
Sodium iodoacetate
powder, ≥98%
Synonym(s):
Iodoacetic acid sodium salt
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About This Item
Linear Formula:
ICH2COONa
CAS Number:
Molecular Weight:
207.93
Beilstein:
4009322
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77
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Product Name
Sodium iodoacetate, ≥98%
biological source
synthetic (organic)
Quality Level
Assay
≥98%
form
powder
mp
208 °C (dec.) (lit.)
solubility
H2O: 100 mg/mL
storage temp.
−20°C
SMILES string
[Na+].[O-]C(=O)CI
InChI
1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1
InChI key
AGDSCTQQXMDDCV-UHFFFAOYSA-M
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Application
Reagent for the modification of cysteine residues in proteins.
Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.
Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.
Biochem/physiol Actions
Used to induce osteoarthritis-like lesions and functional impairment in rats, for testing of chondroprotective agents and diagnostic imaging techniques.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point(F)
406.4 °F
Flash Point(C)
208 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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