P1941

Poly(D,L-lactide-co-glycolide)

lactide:glycolide (75:25), mol wt 66,000-107,000

• Synonym(s): LACTEL^® B6007-1, PLGA
• Linear Formula: [C₃H₄O₂]_x[C₂H₂O₂]_y
• MDL number: MFCD00131930
• UNSPSC Code: 12162002
• PubChem Substance ID: 24898256
• NACRES: NA.26

Properties

• form: pellets
• Quality Level: 100
• feed ratio: lactide:glycolide (75:25)
• mol wt: 66,000-107,000
• storage temp.: −20°C
• SMILES string: OCC(O)=O.CC(O)C(O)=O
• InChI key: XBBVURRQGJPTHH-UHFFFAOYSA-N

Description

General description

The product is an amorphous solid with a transition temperature (Tg) in the range of 45-50°C. It is soluble in most organic solvents such as methylene chloride, tetrahydrofuran, ethyl acetate, acetone, chloroform, and hexafluoroispropanol.

Application

Poly(D,L-lactide-co-glycolide) is a synthetic amino acid that has been used to deliver macromolecular therapeutics.

Features and Benefits

Controlled release of bioactive agents, sutures and bioabsorbable implantable devices.

Physical form

Biocompatible, biodegradable polymer.

Legal Information

Lactel is a registered trademark of Evonik Corp

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves