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R7882

Sigma-Aldrich

Retinyl acetate

solid or viscous liquid, BioReagent, synthetic, suitable for cell culture

Synonym(s):

Retinol acetate, Vitamin A acetate

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100 μG
₩913,602

₩913,602


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100 μG
₩913,602

About This Item

Empirical Formula (Hill Notation):
C22H32O2
CAS Number:
Molecular Weight:
328.49
Beilstein:
1915439
EC Number:
MDL number:
UNSPSC Code:
12352205
eCl@ss:
34058009
PubChem Substance ID:
NACRES:
NA.75

₩913,602


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biological source

synthetic

product line

BioReagent

Assay

≥90% (HPLC)

form

solid or viscous liquid

potency

~2,800,000 I.U. per g

mol wt

Mw 328.49 g/mol

technique(s)

cell culture | mammalian: suitable

color

light yellow to dark yellow

mp

57-58 °C

solubility

absolute ethanol: 25 mg/mL (lit.)

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This Item
R4632R325046958
assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

-

assay

-

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

100

solubility

absolute ethanol: 25 mg/mL (lit.)

solubility

-

solubility

-

solubility

-

mp

57-58 °C

mp

57-58 °C, ~58 °C (lit.)

mp

57-58 °C

mp

57-58 °C

form

solid or viscous liquid

form

crystalline solid or supercooled liquid

form

matrix dispersion

form

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-10 to -25°C

General description

Retinyl-acetate is a natural and ester derivative of vitamin A.[1] It is found in classical media formulations such as M-199; NCTC-109 and William′s Medium E. Vitamin A is a component of serum useful in most serum containing cell culture systems, which receive some level of vitamin A.

Application

Retinyl acetate has been used as a standard to measure the concentration of vitamin C in high performance liquid chromatography analysis (HPLC)[2] and as a supplement in the preparation of the complete medium.[3]

Biochem/physiol Actions

The oxidized form of retinol is retinoic acid, which has hormone-like growth factor and differentiation activity for epithelial and related cell types, especially neural cells. Retinoic acid induces embryonic stem cells to differentiate towards neural cells. Retinyl-acetate is known to be effective in treating breast cancer.[4]

Other Notes

All trans

Preparation Note

The melting point of this material is approx. 58 °C. In order to package, it was melted and may exist as a crystalline solid or as a supercooled viscous liquid.

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Chronic 4 - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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