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SAB1404480

Sigma-Aldrich

Monoclonal Anti-TNF antibody produced in mouse

clone M1-C4, purified immunoglobulin, buffered aqueous solution

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

₹24,040.00

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biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

M1-C4, monoclonal

form

buffered aqueous solution

mol wt

antigen ~51.74 kDa

species reactivity

human

technique(s)

capture ELISA: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL

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BRAND® centrifuge tubes

material

beaded neck tube, polypropylene , round bottom tube, cylindrical tube

material

beaded neck tube, cylindrical tube, polypropylene , round bottom tube

material

beaded neck tube, cylindrical tube, polypropylene , round bottom tube

material

beaded neck neck, cylindrical polypropylene tube, round bottom bottom

manufacturer/tradename

BRAND 115354

manufacturer/tradename

BRAND 115352

manufacturer/tradename

BRAND 115342

manufacturer/tradename

BRAND 115356

packaging

pack of 20 ea

packaging

pack of 20 ea

packaging

pack of 250 ea

packaging

pack of 10 ea

capacity

110 mL

capacity

75 mL

capacity

10 mL

capacity

125 mL

feature

autoclavable at 121°C and withstand RCF of up to 5,000 × g

feature

autoclavable at 121°C and withstand RCF of up to 5,000 × g, without cap

feature

autoclavable at 121°C and withstand RCF of up to 5,000 × g, without cap

feature

autoclavable at 121°C and withstand RCF of up to 5,000 × g, without cap

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

General description

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. (provided by RefSeq)

Immunogen

TNF (AAH28148, 1 a.a. ~ 233 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL

Physical form

Solution in phosphate buffered saline, pH 7.4

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    J1181-S2
    D2071-S2
    DC191-S2
    08127-S2

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