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About This Item
Empirical Formula (Hill Notation):
C17H18N2
CAS Number:
Molecular Weight:
250.34
UNSPSC Code:
12352200
NACRES:
NA.77
Quality Level
Assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 10 mg/mL, clear
storage temp.
−20°C
SMILES string
[nH]1c2c(nc1c3ccc(cc3)C(C)(C)C)cccc2
InChI
1S/C17H18N2/c1-17(2,3)13-10-8-12(9-11-13)16-18-14-6-4-5-7-15(14)19-16/h4-11H,1-3H3,(H,18,19)
InChI key
LQUNNCQSFFKSSK-UHFFFAOYSA-N
Biochem/physiol Actions
ZLN005 is a transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α). ZLN005 increased PGC-1 and downstream gene transcription in skeletal muscle, while reducing hepatic PGC-1α and gluconeogenesis genes. ZLN005 increased fat oxidation and improved the glucose tolerance, pyruvate tolerance, insulin sensitivity, hyperglycemia and dyslipidemia of diabetic db/db mice.
ZLN005 is a transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
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